Fig. 7

In vivo treatment efficacy of nanoassemblies against A549/T xenograft tumors (n = 6). A The tumor growth curves after treated with different formulations. The red arrows indicate the dates of administration. B Body weight changes. C Pictures of extracted tumors after last treatment. D The weights of extracted tumors. E Tumor burden. F Western blot of P-gp, p62, and LC3 expression of the tumors. G–I Quantitative presentations of Western blotting. J The mdr1-gene expression of the tumors by q-PCR analysis. The data are presented as means ± SD. *p < 0.05, **p < 0.01, and ***p < 0.001