Skip to main content
Fig. 3 | Journal of Nanobiotechnology

Fig. 3

From: Antenna-enhanced mid-infrared detection of extracellular vesicles derived from human cancer cell cultures

Fig. 3

a 3D sketch of the nanoantenna array functionalization for EV immunocapture. b Schematic representation of the gold-conjugated molecules. c The ratio between reflectance spectra R(t), taken at time t after antibody exposure at t = 0, and R(0). The colors, from light green to black represent the increasing t from 0 to 32 min with 2-min steps, as shown in the colorbar on the right. The grey line is a representative S-shaped fitting curve used to evaluate the SPR frequency shift. d Detailed view of the different absorption signals in the region of the amide bands (1500–1700 cm−1), with the same color legend of the panel c. e SPR frequency shift vs. time obtained by the fitting procedure of the data in panel c in the 1800–2100 cm−1 range. The solid green line represents the sigmoidal fitting curve. f Integral of the difference in absorption signal in the amide band region vs. t and the related sigmoidal fitting curve

Back to article page