Fig. 4

PDA-PEG NPs regulates osteoclastogenesis-related genes and proteins. a Expression of osteoclast-related genes including NFATC1, TRAP, c-FOS, DC-STAMP, cathepsin K, and CALCR. n = 3. b Expression of NFATC1 protein assessed by western blotting. c Effects of PDA-PEG NPs on NF-κB pathway proteins including p-IκBα/IκBα, p‐p65/p65. d MAPK signaling pathway proteins including p-ERK/ERK, p-JNK/JNK, and p-p38/p38 were evaluated. Symbol “*” denotes p < 0.05, “**” denotes p < 0.01, NS indicates not significant