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Fig. 5 | Journal of Nanobiotechnology

Fig. 5

From: Antioxidant PDA-PEG nanoparticles alleviate early osteoarthritis by inhibiting osteoclastogenesis and angiogenesis in subchondral bone

Fig. 5

PDA-PEG NPs inhibits H2O2-induced osteoclast differentiation. a BMMs treated with various concentrations of H2O2 then assessed by CCK-8. b TRAP staining of BMMs treated with exogenous H2O2 and PDA-PEG NPs on the 3rd day, ×100 magnification. c Quantification of TRAP-positive cells per field. d Effect of PDA-PEG NPs on NFATC1 expression determined by western blotting. n = 3. Symbol “*” denotes p < 0.05, “**” denotes p < 0.01

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