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Fig. 6 | Journal of Nanobiotechnology

Fig. 6

From: Localized DNA tetrahedrons assisted catalytic hairpin assembly for the rapid and sensitive profiling of small extracellular vesicle-associated microRNAs

Fig. 6

A The expression of four sEV-miRNAs measured by the electrochemical platform in gastric cancer cohort (healthy donors, n = 12; patients with gastric cancer in stage I–II, n = 35; stage III–IV, n = 10. B–E The electrochemical signal for sEV-miR-1246, sEV-miR-21, sEV-miR-183-5p and sEV-miR-142-5p profiling in gastric cancer cohort (*p < 0.1; **p < 0.05). F, G ROC curve of single sEV-miRNA and combined sEV-miRNAs for diagnosing patients with gastric tumors. H, I ROC curve of single sEV-miRNA and combined sEV-miRNAs for identifying gastric cancer in early stages (I–II). J–M Plasma samples from gastric cancer patients (n = 9) before (Pre) and after (Post) surgery measured by sEV-miRNAs profiles (J sEV-miR-1246; K sEV-miR-21; L sEV-miR-183-5p; and M sEV-miR-142-5p; **p < 0.05)

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Journal of Nanobiotechnology

ISSN: 1477-3155

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