Fig. 4
The investigation of Co-UiO-67 conjugates in vivo by PET imaging. A Representative PET images of MDA-MB-231 tumor bearing mice injected with 89Zr-Co-UiO-67@Py-PAA-PEG-F3 or 89Zr-Co-UiO-67@Py-PAA-PEG. B The region-of-interest (ROI) analysis of mice images injected with 89Zr-Co-UiO-67@Py-PAA-PEG-F3 (n = 4). C The ROI analysis of mice images injected with 89Zr-Co-UiO-67@Py-PAA-PEG (n = 4). D Tumor uptake comparison between 89Zr-Co-UiO-67@Py-PAA-PEG-F3 (n = 4) and 89Zr-Co-UiO-67@Py-PAA-PEG (n = 4). * p < 0.05. E Organ distribution profiles of 89Zr-Co-UiO-67@Py-PAA-PEG-F3 and 89Zr-Co-UiO-67@Py-PAA-PEG by gamma counting. Red box highlighted the tumor uptake in each group