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Fig. 5 | Journal of Nanobiotechnology

Fig. 5

From: Intensity-adjustable pain management with prolonged duration based on phase-transitional nanoparticles-assisted ultrasound imaging-guided nerve blockade

Fig. 5

A In vivo B-Mode and CEUS-Mode ultrasonic images around the sciatic nerve after injection with RLBP nanoparticles. The circle marks the treated sciatic nerve. B Quantitative analysis of sound intensity in the CEUS-Mode ultrasonic images. C Quantitative analysis of relative fluorescence signal of D NIRF images of the mice treated by the RLBP nanoparticles and the LBP nanoparticles. (n = 3, *p < 0.05, **p < 0.01 compared by Students’ t-test) E NIRF images of the major organs (including heart, liver, spleen, lungs, kidney, and brain) in mice after injection of RLBP and F corresponding quantitative data

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