Table 4 SERS tags using different specific recognition elements for indirect cancer and pathogens diagnosis
From: Nanomaterials meet surface-enhanced Raman scattering towards enhanced clinical diagnosis: a review
Recognition elements | SERS Tags | Reporter | Target analyte/cells | Refs. | |
|---|---|---|---|---|---|
Structure | Morphology | ||||
Antibody |
Antibody-DTNB-Au nanorod |
| DTNB | Staphylococcus aureus | [210] |
Antibody-DTNB-Au@Ag nanorod |
| DTNB | Circulating tumor cells | [211] | |
Aptamer |
Aptamer- conjugated Au |
| DTNB, MBA | Escherichia Coli Staphylococcus aureus | [212] |
Aptamer-DSPE-graphene isolated Au nanocrystals (GLANs) |
| 2D carbon nanomaterials | HepG2, A549 cell lines | [213] | |
MIPs |
MIP-PATP-Ag nanoparticles |
| PATP | Sialic acid (cancer cells and tissues imaging) | [214] |
Antibiotic |
Vancomycin (Van)-MBA-Au |
| MBA | Staphylococcus aureus | [215] |
Luteinizing hormone-releasing hormone (LHRH) |
LHRH-pMBA-Au nanoparticles |
| 4-mercaptobenzoic acid (pMBA) | Circulating tumor cells | [216] |
Transferrin |
Transferrin-BDT-Au |
| 1,4-benzenedi-thiol (BDT) | Hela cell | [217] |
Folic acid |
FA-Au@polyPOPA@Ag |
| Rh6G MB | Human lung adenocarcinoma cell line A549 | [218] |
