From: Nanomaterials meet surface-enhanced Raman scattering towards enhanced clinical diagnosis: a review
Recognition elements | SERS Tags | Reporter | Target analyte/cells | Refs. | |
---|---|---|---|---|---|
Structure | Morphology | ||||
Antibody |
Antibody-DTNB-Au nanorod | DTNB | Staphylococcus aureus | [210] | |
Antibody-DTNB-Au@Ag nanorod | DTNB | Circulating tumor cells | [211] | ||
Aptamer |
Aptamer- conjugated Au | DTNB, MBA | Escherichia Coli Staphylococcus aureus | [212] | |
Aptamer-DSPE-graphene isolated Au nanocrystals (GLANs) | 2D carbon nanomaterials | HepG2, A549 cell lines | [213] | ||
MIPs |
MIP-PATP-Ag nanoparticles | PATP | Sialic acid (cancer cells and tissues imaging) | [214] | |
Antibiotic |
Vancomycin (Van)-MBA-Au | MBA | Staphylococcus aureus | [215] | |
Luteinizing hormone-releasing hormone (LHRH) |
LHRH-pMBA-Au nanoparticles | 4-mercaptobenzoic acid (pMBA) | Circulating tumor cells | [216] | |
Transferrin | Transferrin-BDT-Au | 1,4-benzenedi-thiol (BDT) | Hela cell | [217] | |
Folic acid | FA-Au@polyPOPA@Ag | Rh6G MB | Human lung adenocarcinoma cell line A549 | [218] |