Fig. 6

In vivo antitumor efcacy enabled by HHBP. a The tumor growth curves following diferent treatments (n = 3). ***P < 0.001. b Body weight of 4T1 tumor-bearing mice after diferent treatments (n = 3). c Representative images of the excised tumors after diferent treatments. (I) PBS, (II) HMME@HMONs-PEG, (III) HHBP, (IV) HMME@HMONs-PEG + US, and (V) HHBP + US. d Histological and immunohistochemical analyses of H&E, Ki67 and TUNEL assays for the excised tumor tissues after diferent treatments. Scale bar = 200 μm. e Representative immunofuorescence images of LC3 in the tumor tissues of mice after diferent treatments. Scale bar = 100 μm