Fig. 6
Reproduced from our previous study [30]
Patient-derived retinal organoids recapitulate disease-specific features. A Bright-field images and B H&E staining of control and XLRS patient-derived retinal organoids exhibit schisis feature at day 150 of differentiation. C Quantification of splitting area in control and XLRS-patient-derived retinal organoids. D Bright-field images of control and XLRS patient-derived retinal organoids at days 90, 100, and 110 of differentiation. E A schematic presentation of the time course for the generation of control and XLRS patient-derived retinal organoids. Disease-specific features can be observed after applying defined differentiation stimuli and time course.