Fig. 4

Treg-derived exosomes suppressed microglia pyroptosis. A Representative immunostaining image of IBA1 and GSDMD in the microglia; B Quantification of fluorescence intensity(n = 3); C Morphology of exosomes under TEM (50–150 nm); D NTA analysis exhibit exosomes size; E Western blot analysis of exosome surface markers; F The red fuorescence dye Dil-labeled exosomes was uptaken into microglia