Fig. 7

Treg-Exosomes promote motor function recovery and supress microglia pyroptosis by delivering miR-709 after SCI. A BMS was used to functionally grade mice in indicated groups up to 28 days post-injury; B Rotarod tests analysis of indicated groups at day 28 post-injury; C MEP analysis was used as electrophysiological assessment in indicated groups at Day 28 postinjury; D Quantification of peak-to-peak MEP amplitudes and latencies in indicated groups (n = 6); E Representative immunofluorescence images for GSDMD(pyroptosis) and IBA1(microglia) expression in indicated groups at Day 7 postinjury; F Quantification of fluorescence intensity at Day 7 postinjury (n = 3)