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Fig. 2 | Journal of Nanobiotechnology

Fig. 2

From: A novel structurally identified epitope delivered by macrophage membrane-coated PLGA nanoparticles elicits protection against Pseudomonas aeruginosa

Fig. 2

Screening for immunogenic epitopes in serum samples provided by patients who had recovered from PA infection. A. Heatmap of the reactivities of 54 peptides (corresponding to those in the predicted extracellular loops) to the sera from 10 recovered patients and 10 healthy donors. B. The responses of the peptides to the serum samples clustered according to the individual transmembrane proteins. The bar represents the median fluorescence intensity (MFI) of each peptide determined using the Luminex assay. The top 10 most immunoreactive peptides are labeled with a blue background. Multiple comparisons among recovered patients and healthy donors in each group were analyzed by two-way ANOVA. *P < 0.05

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