Fig. 1
Preparation and characterization of mRNA@cRGD-CM-CaCO3 NPs. A TEM image of mRNA@CaCO3 NPs cores. B TEM image of mRNA@CaCO3 NPs cores coated with cRGD-CM shells (mRNA@cRGD-CM-CaCO3 NPs). Arrows show the shells surrounding the cores. C, D Size and zeta potential measurement of mRNA@CaCO3 NPs and mRNA@cRGD-CM-CaCO3 NPs. (E) Energy-dispersive X-ray spectroscopy (EDS) elemental mapping of mRNA@cRGD-CM-CaCO3 NPs. Data are expressed as mean ± SEM (n = 5). *P < 0.05, **P < 0.01