Fig. 5
In vivo anti-glioma activity of IL-12 mRNA@cRGD-CM-CaCO3 NPs. A Representative bioluminescence images of GL261-Luc glioma-bearing mice in different groups. B Quantitative analysis of bioluminescence signal intensity. C Survival curve for the mice (n = 5 mice per group). D IL-12 and IFN-γ expression in tumors from immunized mice. Data are expressed as mean ± SEM (n = 5). ND, not detected. **P < 0.01, ***P < 0.001