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Fig. 7 | Journal of Nanobiotechnology

Fig. 7

From: TSPAN4-positive migrasome derived from retinal pigmented epithelium cells contributes to the development of proliferative vitreoretinopathy

Fig. 7

Illustration of migrasome characteristics in proliferative vitreoretinopathy (PVR). Mechanically, the induction of TGF-β1 causes the up-regulation of TSPAN4. The migrasome was then generated in a Alix-associated pathway. Morphologically, the transformation of RPE cells and the formation of vesicles are shown under PVR microenvironment

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