Fig. 7From: TSPAN4-positive migrasome derived from retinal pigmented epithelium cells contributes to the development of proliferative vitreoretinopathy Illustration of migrasome characteristics in proliferative vitreoretinopathy (PVR). Mechanically, the induction of TGF-β1 causes the up-regulation of TSPAN4. The migrasome was then generated in a Alix-associated pathway. Morphologically, the transformation of RPE cells and the formation of vesicles are shown under PVR microenvironmentBack to article page