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Fig. 1 | Journal of Nanobiotechnology

Fig. 1

From: Extracellular matrix modulating enzyme functionalized biomimetic Au nanoplatform-mediated enhanced tumor penetration and synergistic antitumor therapy for pancreatic cancer

Fig. 1

Characterization of Col-M@AuNCs/Dox. a TEM images of AgNCs (1), AuNCs (2) and M@AuNCs/Dox (3). b UV‒Vis absorption spectra of AgNCs and AuNCs. c Hydrodynamic diameters and polydispersity index (PDI) of AuNCs, AuNCs/Dox, M@AuNCs/Dox and Col-M@AuNCs/Dox. d Zeta potentials of AuNCs, AuNCs/Dox, M@AuNCs/Dox and Col-M@AuNCs/Dox. e Relative enzyme activities of free collagenase, DSPE-PEG-Col and Col-M@AuNCs/Dox. f Hydrodynamic diameter and zeta potential stability of Col-M@AuNCs/Dox. g Western blotting analysis of the proteins from BxPC3 cells, BxPC3 cell membranes and M@AuNCs/Dox. h–i FCM analysis of the cellular uptake of M@AuNCs/Dox into H22, B16, 4T1 and BxPC3 cells and the quantitative analysis of fluorescence intensity

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