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Fig. 7 | Journal of Nanobiotechnology

Fig. 7

From: Different coatings on magnetic nanoparticles dictate their degradation kinetics in vivo for 15 months after intravenous administration in mice

Fig. 7

Evolution of the degradation of the APS, DEX and DMSA coated MNPs in the spleen as measured at different times by the AC magnetic susceptibility. The magnetic susceptibility profiles of the spleen extracted from the mice to which the different MNPs were administered: a, APS-MNPS; b, DEX-MNPs; and c, DMSA-MNPs. The signal corresponding to ferritin is indicated in the degradation profile of the different MNPs (upper left corner of the χ′′ profile). The different degradation times after the last dose administered are represented in the following colors: 7 days (purple), 14 days (cyan), 1 month (pink), 3 months (orange), 6 months (blue), 9 months (green), 12 months (black) and finally 15 months (gray). The in-phase (real, χ′- on the left) and out-of-phase (imaginary, χ′′- on the right) components of the AC magnetic susceptibility measurements are shown

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