Fig. 5
From: Noninvasive prenatal diagnosis targeting fetal nucleated red blood cells
Copyright 2020 Springer Nature b FISH for detection of fetal T13, T18, and T21. Reprinted with permission from ref [39]. Copyright 2017 The Author(s). c FISH and STR analysis for a female fetus to confirm the cellular origin. Reprinted with permission from ref [38]. Copyright The Royal Society of Chemistry 2021 d PCR for detection of fetal blood group. Reprinted with permission from ref [28]. Copyright 2019 John Wiley & Sons. e Detection of fetal aneuploidy disorders using aCGH and NGS. Reprinted with permission from ref [39]. Copyright 2017 Springer Nature. f WGS for detection of fetal-associated disease variants. Reprinted with permission from ref [222]. Copyright 2017 John Wiley & Sons
Clinical applications of fNRBCs. a Three-color immunofluorescence identification and FISH for detecting the cellular origin of male fetuses. Reprinted with permission from ref [14].