Table 1 IC50 and TI of free TNF, AuNPs, and AuNP-TNF in TZM-bl & PBMCs
Sr. No | Compound name | Anti–HIV1 assay TZM-bl cells | Anti–HIV1 assay PBMCs | ||||||
|---|---|---|---|---|---|---|---|---|---|
IC50 HIV1VB28 (R5) (μg/mL) | TI HIV1VB28 (R5) | IC50 HIV1UG070 (X4) (μg/mL) | TI HIV1UG070 (X4) | IC50 HIV1VB28 (R5) (μg/mL) | TI HIV1VB28 (R5) | IC50 HIV1UG070 (X4) (μg/mL) | TI HIV1UG070 (X4) | ||
1 | TNF | 0.771 ± 0.080 | 264.68 | 0.570 ± 0.196 | 358.29 | 0.394 ± 0.053 | 364.31 ± 30.48 | 0.560 ± 0.083 | 255.35 ± 5.19 |
2 | AuNPs | 1.745 ± 0.187 | 149.12 | 2.427 ± 0.079 | 107.20 | 1.171 ± 0.067 | 196.23 ± 8.32 | 0.1993 ± 0.039 | 115.01 ± 3.6 |
3 | AuNP-TNF | 0.026 ± 0.005 | 15,178.53 (***) | 0.037 ± 0.008 | 10,796.86 (***) | 0.016 ± 0.004 | 22,897.63 ± 6375.34 (***) | 0.030 ± 0.005 | 11,332.61 ± 2198.59 (***) |