Fig. 3
From: Acidic and hypoxic tumor microenvironment regulation by CaO2-loaded polydopamine nanoparticles
Antitumor effect study in 4T1 tumor models. A Diagrammatic representation of the therapeutic experiment (n = 5, mean ± SD). Tumor inoculation and intravenous injections were performed as described. B Comparison of tumor growth profiles in different treatments. C Average tumor weight after various treatment. D Mice weight changes during different treatments. E Tumor lactic acid concentration after different treatments. F Immunofluorescence staining of GLUT1, HIF-1α, and LDHA, respectively (Green: antibody, Blue: DAPI, Scale bar: 50 μm). G–I The corresponding quantitative expression analyses of F