Fig. 4

In vivo anti-breast tumor effects of TLNTs. A Body weight variations and B tumor growth curves of different mouse groups with various treatments during the whole experimental period. C Tumor weights, D representative tumor images and E spleen weights of different mouse groups with various treatments at the end of the experiment. Each point represents the mean ± S.E.M. (n = 5; *p < 0.05, **p < 0.01, ***p < 0.001 and ns no significance). F H&E- and TUNEL-stained tumor sections showing pathological changes and apoptosis profiles (scale bar: 100 μm)