Fig. 4From: A pH-responsive metal-organic framework for the co-delivery of HIF-2α siRNA and curcumin for enhanced therapy of osteoarthritisRelative mRNA levels of chondrogenic markers (Acan, Col2a1, and SOX9), OA-relative genes (MMP3, MMP13, HIF-2α, IL-6, Adamts-5, and COX-2). Data are presented herein as the mean ± SD (n = 3). *p < 0.05; **p < 0.01; ***p < 0.001Back to article page