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Fig. 1 | Journal of Nanobiotechnology

Fig. 1

From: Phosphorothioated amino-AS1411 aptamer functionalized stealth nanoliposome accelerates bio-therapeutic threshold of apigenin in neoplastic rat liver: a mechanistic approach

Fig. 1

Drug-excipients interaction and aptamer conjugation on stealth nanoliposome. a FTIR spectra of apigenin (A), soya lecithin (B), cholesterol (C), DSPE-PEG-2000-COOH (D), BHT (E), Blank formulation (F), the physical mixture of all constituents (G), NLCs (H), PEG-NLCs (I), and Apt-NLCs (J); b Pictorial representation of surface functionalization of PEG-NLCs with modified NH2-AS1411; c Determination of aptamer conjugation by agarose gel. The first three lanes from the left had (Apt-NLCs) showing no sample run, the 4th lane showed free aptamer (AS1411) showing movement, and the 5th lane had DNA ladder; d i, ii, iii represented spectrometric reading for free AS1411, plain nanoliposomes AS1411 conjugated nanoliposomes by nanodrop UV spectrophotometer, (experiment was conducted on triplicate set)

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Journal of Nanobiotechnology

ISSN: 1477-3155

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