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Fig. 4 | Journal of Nanobiotechnology

Fig. 4

From: Phosphorothioated amino-AS1411 aptamer functionalized stealth nanoliposome accelerates bio-therapeutic threshold of apigenin in neoplastic rat liver: a mechanistic approach

Fig. 4

Cellular uptake studies. Flow cytometric data of cellular uptake. a PEG-NLCs, b Apt-NLCs, c Apt-NLCs in the presence of free AS1411 (receptor blocking condition) in Hep G2 cells at 1h, 2h, and 4h d Histogram representation of FACS mean fluorescence values obtained through above-mentioned uptake studies. Data represents mean ± SD, (n=3), bar (-) indicates groups between which the comparisons were made. ns: statistically insignificant, *** refer statistical significance at a level of P<0.05. e and f Confocal microscopic images of cell uptake of PEG-NLCs and Apt-NLCs in Hep G2 at 1h and 4h (Green color shows for FITC-labelled experimental nanoliposomes, PEG-NLCs/ Apt-NLCs, and blue color indicates nucleus stained by DAPI

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