Fig. 4

Biosafety evaluation. a The mean size of THGP in various suspensions (inset: corresponding digital images). b Hemolysis analysis of HGP and THGP (inset: corresponding digital images) (n = 3). c In vitro fluorescence imaging intensity of DIR-labeled THGP (inset: corresponding fluorescence images) (n = 3). d and e Routine blood analyses on various days after intravenous injection of THGP (n = 5). (f) Blood biochemical analyses of the blood on various days after intravenous injection of THGP (n = 5). g In vivo metabolic fluorescence images after intravenous injection with THGP and HGP for various time intervals. h H&E staining of major organs on various days after intravenous injection of THGP (scale bar: 200 μm)