Fig. 6

US imaging. a Illustration of the ADV process of USI. b In vitro echo intensity in B-mode (n = 3), d echo intensity in CEUS-mode (n = 3); and c the corresponding US images when THGP was treated with different LIFU-time and power conditions. e Optical microscopy images of the ADV process when THGP was treated with LIFU. f In vivo echo intensity in the B-mode (n = 3); g echo intensity in CEUS-mode (n = 3); and h the corresponding US images 2 h after intravenous injection with THGP or HGP. The tumors were exposed to LIFU