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Fig. 8 | Journal of Nanobiotechnology

Fig. 8

From: Endothelial cell-derived exosomes boost and maintain repair-related phenotypes of Schwann cells via miR199-5p to promote nerve regeneration

Fig. 8

Immunofluorescence analysis of sciatic nerves. A NF200/S100β and B TuJ1/MBP double immunofluorescence staining of sciatic nerve longitudinal sections at 28 days following the operation. Nuclei were stained with DAPI. Scale bar, 20 μm. C-F The statistical results of percentages of positive. NF200, S100β, TuJ1 and MBP in sham, PNI and EXO groups. The data are expressed as mean ± SD (n = 3). G, H Representative immunofluorescence images of sciatic nerve cross-sections stained with NF200/S100β and TuJ1/MBP. Nuclei were stained with DAPI. Scale bar, 20 μm. I–L Statistical analysis of different groups. The data are expressed as mean ± SD (n = 3). M Representative images of immunofluorescence staining for CD31, CD34 and VEGFR of sciatic nerve cross-sections in each group. Nuclei were stained with DAPI. Scale bar, 100 μm. N Statistical analysis of vessel area. The data are expressed as mean ± SD (n = 3). *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.

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