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Fig. 8 | Journal of Nanobiotechnology

Fig. 8

From: Customizing delivery nano-vehicles for precise brain tumor therapy

Fig. 8

a β-glucans, a kind of prodrug, have a specific chemical makeup and structural arrangement [73]. b In ex vivo images, fluorescence-labeled prodrug nanoparticles were shown to be colocalized with M cells, macrophages, and the brain [73]. c Fluorescence-labeled prodrug nanoparticles being taken up by RAW264.7 macrophages in vitro (using the dectin-1 receptor) [73]; d Real-time IVIS pictures demonstrating accumulation of f-prodrug nanoparticles in brain tumor (ALTS1C1) collected at designated times following oral treatment to mice [73]. And quantities of the drug (TMZ) discovered in organs 6 h after therapy. I, the brain; II, the heart; III, the lungs; IV, the liver; V, the spleen; VI, the pancreas; and VII, the kidneys

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