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Fig. 2 | Journal of Nanobiotechnology

Fig. 2

From: Ultrasound targeted microbubble destruction-triggered nitric oxide release via nanoscale ultrasound contrast agent for sensitizing chemoimmunotherapy

Fig. 2

UTMD combined with NDs elicit the release of NO. A ROS level after various treatments quantified by FCM. B The percentage of ROS production rate obtained from A. C NO level after various treatments quantified by FCM. D The percentage of NO release rate obtained from C. E Fluorescence images of ROS generation (DCFH-DA, green) post different treatments. Scale bar: 200 μm. F Fluorescence images of NO release stained with DAF-FM (green) in various treatments. Scale bar: 200 μm. G Fluorescence images of NO release (DAF-FM, green) post-treatment (Control, ND + US, ND + US + NAC). Scale bar: 200 μm. H NO level post-treatment (Control, ND + US, ND + US + NAC) quantified by FCM. I The percentage of NO level obtained from H. Data are presented as mean ± SD (n = 3, *p < 0.05, **p < 0.01)

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