Fig. 7From: Ultrasound targeted microbubble destruction-triggered nitric oxide release via nanoscale ultrasound contrast agent for sensitizing chemoimmunotherapyIn vivo antitumor effect. A Schematic diagram of animal experiment. B Body weight of mice at various groups. C Photographs of isolated tumors at day 12. The white circle marked that the tumor achieved complete cure during the treatment. D Tumor growth in different groups. E Tumor weight in each group. F HE, TUNEL, and Ki67 staining of tumor sections at the end of experiment. TUNEL positive: green, and cell nuclei stained by DAPI was blue in the fluorescent mode. Scale bar: 200 µm (HE); 100 µm (TUNEL, Ki67). Data are presented as mean ± SD (n = 5, *p < 0.05, **p < 0.01)Back to article page