Fig. 1
Synthesis and Characterization of HCR NPs and in vitro cellular uptake. A The Tyndall effect of HCR NPs. B Size distribution of HCR NPs. C UV–vis absorption spectra of HCR NPs. D Zeta potential of HCR NPs. E TEM image of HCR NPs. Scale bar: 100 nm. F The release of CLT at pH 5.0 and 7.4. G, H The photothermal activity of IR820 and HCR NPs dispersed in water at various concentrations (λ = 808 nm, P = 1 W/cm2; 5 min). I-K Flow cytometric results of the cellular uptake of HCR NPs in DLD-1, HCT116, and LO2 cells after incubation for the indicated times