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Fig. 1 | Journal of Nanobiotechnology

Fig. 1

From: Berberin sustained-release nanoparticles were enriched in infarcted rat myocardium and resolved inflammation

Fig. 1

Characterization of the platelet (PLT) membrane-coated biomimetic nanoparticles and ex vivo fluorescence imaging of isolated major organs. a Transmission electron microscopy images of BBR@PLGA and BBR@PLGA@PLT NPs (scale bar = 200 nm). b The sizes and c zeta potentials of BBR@PLGA and BBR@PLGA@PLT NPs. d The trends of sizes and zeta potentials of BBR@PLGA@PLT NPs over time. e In vitro drug release profiles of BBR@PLGA and BBR@PLGA@PLT NPs. f Ex vivo fluorescence imaging of the heart and the other major organs (liver, kidney, spleen, and lung) of MI rats 24 h after DSPE-PEG2000-Cy7-labelled BBR@PLGA@PLT administration. All bars represent as means ± SD (n = 3)

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