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Fig. 1 | Journal of Nanobiotechnology

Fig. 1

From: Apoptotic tumor cell-derived microparticles loading Napabucasin inhibit CSCs and synergistic immune therapy

Fig. 1

Bioinformatics analysis of the antitumor effect of NAP. A The analysis of the quality control of RNA sequencing. B The change in the number of genes after NAP treatment. C After the NAP treatment, the tumor stem cell markers, CD44, and BMI1 were significantly down-regulated. D The expression of CD44 in colon cancer patient tissues. E The expression of BMI1 in colon cancer patient tissues. F Changes of many biological processes after NAP treatment. G GSEA algorithm was used to analyze the changes in the JAK-STAT pathway after NAP treatment. H Significant changes in the expression levels of genes involved in the JAK-STAT pathway. I PPI network of 100 genes with the most significant changes. J The top 10 hub genes

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Journal of Nanobiotechnology

ISSN: 1477-3155

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