Fig. 3
From: Near-infrared light triggered in situ release of CO for enhanced therapy of glioblastoma
In vitro assessment of therapeutic efficiency. a Calcein-AM/PI staining assay of U87MG cells treated with UCNPs@Ce6/3HBQ or UCNPs@Ce6 and irradiated with or without 808-nm laser (0.8 W/cm2, 5 min). Scale bar: 50 μm. b Cell viabilities of U87MG cells after incubated with different concentrations of UCNPs@Ce6 or UCNPs@Ce6/3HBQ and irradiated with or without 808-nm laser (0.8 W/cm2, 5 min). c JC-1 staining of U87MG cells treated with UCNPs@Ce6 or UCNPs@Ce6/3HBQ and irradiated with or without 808-nm laser (0.8 W/cm2, 5 min). Scale bar: 20 μm. d Apoptosis analysis of U87MG cells after different treatments by flow cytometry. e Percentage of viable cells, early apoptosis, late apoptosis and necrosis obtained from d