Fig. 4
Detection of SARS-CoV-2 RNA load in the respiratory tract of liposome-based SARS-CoV-2 RBD and N proteins or mRNA vaccinated, and virus challenged ferrets. One-year-old male ferrets were vaccinated twice at 3 weeks interval intranasally with liposomes entrapped SARS-CoV-2 RBD and N proteins or mRNA and monosodium urate crystal adjuvant and challenged with SARS-CoV-2 intranasally. The samples of respiratory tract tissue/fluid: A, E Nasal turbinates, B, F Trachea, C, G BAL fluid, and D, H Lungs collected at DPC 14 were measured for viral RNA load expressed in log10 RNA copies per gram tissue or per mL fluid. Each bar is the mean of 3 animals ± SEM