Enhanced mucosal immune responses and reduced viral load in the respiratory tract of ferrets to intranasal lipid nanoparticle-based SARS-CoV-2 proteins and mRNA vaccines

Table 1 Characterization of liposome formulations for loading efficiency, size and polydisersity index

Vaccine type	Loading efficiency percent	Mean	Median	Polydispersity Index
Vaccine type	Loading efficiency percent	Particle size (nm)	Particle size (nm)	Polydispersity Index
NP-COVID-RBD protein	90	607.1	568.3	0.718
NP-COVID-N protein	92	611.2	618.6	0.7021
NP-COVID-RBD mRNA	88	140.1	146.2	0.1921
NP-COVID-N mRNA	88	147.6	146.0	0.1061

ISSN: 1477-3155