Fig. 2
From: Bosutinib high density lipoprotein nanoformulation has potent tumour radiosensitisation effects
In vitro radiosensitisation properties of bosutinib-HDL NPs. A Cell cycle analysis using fucci-UM-SCC-1 cells. Cells were imaged 24 h after radiation treatment (n = 8). The scale bar is 200 µm. Data is represented as the mean in the graph. B ATP content in UM-SCC-1 cells measured by CellTiter-Glo® assay 48 h after radiation (n = 5). C ATP content in U87 cells measured by CellTiter-Glo® assay 72 h after radiation (n = 6). D Ki-67 expression in UM-SCC-1 cells 48 h after radiation. Data is represented as mean ± standard error of mean. E Effect of bosutinib-HDL NPs on apoptosis in UM-SCC-1 cells. Caspase 3/7 activity 24 h after radiation (n = 7, 8). The scale bar is 200 µm. Two way ANOVA and Tukey multiple comparisons test were used for statistical analysis (α = 0.05)