Fig. 2

The ability of CeO₂–MnO₂ to catalyze hydrogen peroxide, depletion of GSH, rise in ROS induced by radiotherapy, and MRI properties. A Schematic diagram of CeO₂–MnO₂ catalyze hydrogen peroxide, depletion of GSH and promotion of radiotherapy-induced ROS rise and in vitro imaging. B Rates of hydrogen peroxide scavenging by CeO₂–MnO₂ under different concentrations. C The amount of O₂ catalyzed by co-incubation of CeO₂–MnO₂ with 0.1 μg/mL hydrogen peroxide for 15 min. D ESR analysis of •OH production of CeO₂, MnO₂ and CeO₂–MnO₂. (E) ESR analysis of •OH production of CeO₂, MnO₂ and CeO₂–MnO₂ under X-ray (8 Gy). F Quantification of •OH production rate in the presence (8 Gy) and absence of radiotherapy. G UV absorption of CeO₂–MnO₂ after interaction with different concentrations of GSH and pictures of CeO₂–MnO₂ after interaction with different concentrations of GSH. H T1 relaxation rate associated with CeO₂–MnO₂ concentration in the presence of GSH. I T1-weighted photographs of different concentrations of CeO₂–MnO₂ in the presence or absence of GSH