Fig. 5

In vivo antitumor effect of CeO₂–MnO₂ combined with X-ray. A Schematic diagram of the animal experiment. B In vivo T1-weighted MRI images of tumor-bearing mice after intravenous injection of CeO₂–MnO₂ at different periods. C T1 values of tumor-bearing mice after intravenous injection of CeO₂–MnO₂ at different periods. D The body weight during 21 days treatment. E Tumor relative volume curves during 21 days. F Relative tumor weight after 21 days treatment. G Photos of tumors after 21 days treatment. H H&E-stained in tumor regions of different treatment groups by IHC and immunofluorescence analysis of the expression of VEGF, Ki67 and HIF-1α; scale bar = 200 µm