Fig. 6From: Evolocumab loaded Bio-Liposomes for efficient atherosclerosis therapy(E)The number of migrated VSMCs. Images (F) and quantitative (G) of wound-healing assay of VSMCs with different treatments. Scale bars = 200 µm. Data are means ± SD, n = 3, ##P < 0.01, ###P < 0.001 vs. the Control. *P < 0.05, **P < 0.01, ***P < 0.001 vs. the Model(Lipo + M)@E NPs inhibit VSMCs proliferation and migration. (A) The proliferative VSMCs were determined by EdU incorporation assay. Blue represents nuclei and green represents the EdU-positive VSMCs. Scale bars = 60 µm. (B) Viability assay of VSMCs with different treatments. (C) The ratio of EdU-positive cells to total cells under different treatments. (D) Migrated VSMCs were detected by transwell assay. Scale bars = 200 µm.Back to article page