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  1. The advancement of microfluidics has enabled numerous discoveries and technologies in life sciences. However, due to the lack of industry standards and configurability, the design and fabrication of microfluid...

    Authors: Jialin Wu, Hui Fang, Jun Zhang and Sheng Yan
    Citation: Journal of Nanobiotechnology 2023 21:85
  2. Glaucoma is a leading cause of irreversible visual impairment and blindness, affecting over 76.0 million people worldwide in 2020, with a predicted increase to 111.8 million by 2040. Hypotensive eye drops rema...

    Authors: Yuening Shen, Jianguo Sun and Xinghuai Sun
    Citation: Journal of Nanobiotechnology 2023 21:84
  3. In this study, exosomes from cooked meat were extracted by ultra-high-speed centrifugation. Approximately 80% of exosome vesicles were within 20–200 nm. In addition, the surface biomarkers of isolated exosomes...

    Authors: Linyuan Shen, Jianfeng Ma, Yiting Yang, Tianci Liao, Jinyong Wang, Lei Chen, Shunhua Zhang, Ye Zhao, Lili Niu, Xiaoxia Hao, Anan Jiang, Xuewei Li, Mailin Gan and Li Zhu
    Citation: Journal of Nanobiotechnology 2023 21:83
  4. Glycol chitosan nanoparticles (CNPs) have emerged as an effective drug delivery system for cancer diagnosis and treatment. Although they have great biocompatibility owing to biodegradable chemical structure an...

    Authors: Hyeyoun Chang, Ji Young Yhee, Sangmin Jeon, Man Kyu Shim, Hong Yeol Yoon, Sangmin Lee and Kwangmeyung Kim
    Citation: Journal of Nanobiotechnology 2023 21:82
  5. Endometriosis is an estrogen-dependent chronic inflammatory disease. Hormonal and surgical treatments are the most commonly used clinical therapies, but they have many sides effects or are traumatic to the bod...

    Authors: Shasha Zhu, Jiqian Zhang, Nairui Xue, Xiaoling Zhu, Fenfen Li, Qingqing Dai, Xin Qing, Dawei Chen, Xuesheng Liu, Zhaolian Wei and Yunxia Cao
    Citation: Journal of Nanobiotechnology 2023 21:81
  6. Treatment of complete loss of skin thickness requires expensive cellular materials and limited skin grafts used as temporary coverage. This paper presents an acellular bilayer scaffold modified with polydopami...

    Authors: Katarína Kacvinská, Veronika Pavliňáková, Petr Poláček, Lenka Michlovská, Veronika Hefka Blahnová, Eva Filová, Martin Knoz, Břetislav Lipový, Jakub Holoubek, Martin Faldyna, Zdeněk Pavlovský, Monika Vícenová, Michaela Cvanová, Jiří Jarkovský and Lucy Vojtová
    Citation: Journal of Nanobiotechnology 2023 21:80
  7. Most pregnancy losses worldwide are caused by implantation failure for which there is a lack of effective therapeutics. Extracellular vesicles are considered potential endogenous nanomedicines because of their...

    Authors: Linjun Hong, Xupeng Zang, Qun Hu, Yanjuan He, Zhiqian Xu, Yanshe Xie, Ting Gu, Huaqiang Yang, Jie Yang, Junsong Shi, Enqin Zheng, Sixiu Huang, Zheng Xu, Dewu Liu, Gengyuan Cai, Zicong Li…
    Citation: Journal of Nanobiotechnology 2023 21:79
  8. Plant-derived nanovesicles (PDNVs) have been proposed as a major mechanism for the inter-kingdom interaction and communication, but the effector components enclosed in the vesicles and the mechanisms involved ...

    Authors: Jinfeng Liu, Jiaxin Xiang, Cuiyuan Jin, Lusha Ye, Lei Wang, Yanan Gao, Nianyin Lv, Junfeng Zhang, Fuping You, Hongzhi Qiao and Liyun Shi
    Citation: Journal of Nanobiotechnology 2023 21:78
  9. Nanomedicine technology is a rapidly developing field of research and application that uses nanoparticles as a platform to facilitate the diagnosis and treatment of diseases. Nanoparticles loaded with drugs an...

    Authors: Nannan Zhang, Bin Ru, Jiaqi Hu, Langhai Xu, Quan Wan, Wenlong Liu, WenJun Cai, Tingli Zhu, Zhongwei Ji, Ran Guo, Lin Zhang, Shun Li and Xiangmin Tong
    Citation: Journal of Nanobiotechnology 2023 21:77
  10. Intervertebral disc degeneration (IDD) has been identified as one of the predominant factors leading to persistent low back pain and disability in middle-aged and elderly people. Dysregulation of Prostaglandin...

    Authors: Yunhao Wang, Genjiang Zheng, Xiaoxing Xie, Wei Yu, Jianxi Wang, Fazhi Zang, Chen Yang, Qiangqiang Xiao, Rongcheng Zhang, Leixin Wei, Xiaodong Wu, Lei Liang, Peng Cao, Chen Xu, Jing Li, Bo Hu…
    Citation: Journal of Nanobiotechnology 2023 21:76
  11. In recent years, the rapid development of nanotechnology has made significant impacts on the industry. With the wide application of nanotechnology, nanoparticles (NPs) are inevitably released into the environm...

    Authors: Mingyang Gao, Jia Chang, Zhongtang Wang, Hongyan Zhang and Tian Wang
    Citation: Journal of Nanobiotechnology 2023 21:75
  12. Innate immune cells are critical in antitumor immune surveillance and the development of antitumor adaptive cellular immunity. Trained innate immune cells demonstrate immune memory-like characteristics, produc...

    Authors: Duo Li, Weiran Li, Peng Zheng, Ying Yang, Qingwen Liu, Yongmao Hu, Jinrong He, Qiong Long and Yanbing Ma
    Citation: Journal of Nanobiotechnology 2023 21:74
  13. The development of multidrug resistance (MDR) during postoperative chemotherapy for colorectal cancer substantially reduces therapeutic efficacy. Nanostructured drug delivery systems (NDDSs) with modifiable ch...

    Authors: Manman Pei, Kaiyuan Liu, Xiao Qu, Kairuo Wang, Qian Chen, Yuanyuan Zhang, Xinyue Wang, Zheng Wang, Xinyao Li, Feng Chen, Huanlong Qin and Yang Zhang
    Citation: Journal of Nanobiotechnology 2023 21:72
  14. Sustained retina drug delivery and rational drug combination are considered essential for enhancing the efficacy of therapy for wet age-related macular degeneration (wAMD) due to the conservative structure of ...

    Authors: Wenting Su, Congyan Liu, Xi Jiang, Yanli Lv, Qin Chen, Jiachen Shi, Huangqin Zhang, Qiuling Ma, Chang Ge, Fei Kong, Xiaoqi Li, Yuping Liu, Yan Chen and Ding Qu
    Citation: Journal of Nanobiotechnology 2023 21:71
  15. Blood–brain barrier (BBB) disruption is a major adverse event after ischemic stroke (IS). Caveolin-1 (Cav-1), a scaffolding protein, played multiple roles in BBB permeability after IS, while the pros and cons ...

    Authors: Yiyang Li, Bowen Liu, Tingting Zhao, Xingping Quan, Yan Han, Yaxin Cheng, Yanling Chen, Xu Shen, Ying Zheng and Yonghua Zhao
    Citation: Journal of Nanobiotechnology 2023 21:70
  16. The rapid increase in production and application of carbon nanotubes (CNTs) has led to wide public concerns in their potential risks to human health. Single-walled CNTs (SWCNTs), as an extensively applied type...

    Authors: Xiang Zhang, Xinxin Hu, Yuqing Zhang, Bin Liu, Haihong Pan, Zikai Liu, Zhuomeng Yao, Qixing Zhu, Changhao Wu and Tong Shen
    Citation: Journal of Nanobiotechnology 2023 21:69
  17. Hepatocellular carcinoma (HCC) has the sixth-highest new incidence and fourth-highest mortality worldwide. Transarterial chemoembolization (TACE) is one of the primary treatment strategies for unresectable HCC...

    Authors: Gang Yuan, Zhiyin Liu, Weiming Wang, Mengnan Liu, Yanneng Xu, Wei Hu, Yao Fan, Xun Zhang, Yong Liu and Guangyan Si
    Citation: Journal of Nanobiotechnology 2023 21:68
  18. Protein nanostructures produced through the self-assembly of individual subunits are attractive scaffolds to attach and position functional molecules for applications in biomaterials, metabolic engineering, ti...

    Authors: Daniel L. Winter, Hélène Lebhar, Joshua B. McCluskey and Dominic J. Glover
    Citation: Journal of Nanobiotechnology 2023 21:66
  19. Biodegradable polymers are expected to be an alternative to plastics. Because of its high biocompatibility, poly (lactic-co-glycolic acid) (PLGA) is widely used in medicine. It has been reported that micro-nan...

    Authors: Wen Shi, Atik Rohmana Maftuhatul Fuad, Yanhong Li, Yang Wang, Junyang Huang, Ruolin Du, Guixue Wang, Yazhou Wang and Tieying Yin
    Citation: Journal of Nanobiotechnology 2023 21:65

    The Correction to this article has been published in Journal of Nanobiotechnology 2023 21:92

  20. Mild-temperature photothermal therapy (mild PTT) is a safe and promising tumor therapeutic modality by alleviating the damage of healthy tissues around the tumor due to high temperature. However, its therapeut...

    Authors: Kaiyuan Liu, Li Zhang, Hengli Lu, Yingfei Wen, Bo Bi, Guocheng Wang, Yingying Jiang, Leli Zeng and Jing Zhao
    Citation: Journal of Nanobiotechnology 2023 21:64
  21. Acute kidney injury (AKI) refers to a tricky clinical disease, known by its high morbidity and mortality, with no real specific medicine for AKI. The carbonization product from Pollen Typhae (i.e., Pu-huang in Ch...

    Authors: Xiaoke Wang, Tong Wu, Yingxin Yang, Long Zhou, Shuxian Wang, Jiaxing Liu, Yafang Zhao, Meiling Zhang, Yan Zhao, Huihua Qu, Hui Kong and Yue Zhang
    Citation: Journal of Nanobiotechnology 2023 21:63
  22. Guided bone regeneration (GBR) is widely used in treating oral bone defects to exclude the influence of non-osteogenic tissue on the bone healing process. The traditional method of GBR with a titanium mesh to ...

    Authors: Jiaxin Li, Weichang Li, Mengjie Kong, Zongtai Li, Tao Yang, Qinmei Wang and Wei Teng
    Citation: Journal of Nanobiotechnology 2023 21:62
  23. As a consequence of the aggressive and recurrent nature of melanoma, repeated, multimodal treatments are often necessary to cure the disease. While microneedle (MN)-based transdermal drug delivery methods can ...

    Authors: Fan Liu, Zeneng Cheng and Hanxi Yi
    Citation: Journal of Nanobiotechnology 2023 21:61
  24. Unlike the injectable vaccines, intranasal lipid nanoparticle (NP)-based adjuvanted vaccine is promising to protect against local infection and viral transmission. Infection of ferrets with SARS-CoV-2 results...

    Authors: Patricia A. Boley, Carolyn M. Lee, Jennifer Schrock, Kush Kumar Yadav, Veerupaxagouda Patil, Raksha Suresh, Songqing Lu, Maoqi Mark Feng, Juliette Hanson, Rudra Channappanavar, Scott P. Kenney and Gourapura J. Renukaradhya
    Citation: Journal of Nanobiotechnology 2023 21:60
  25. Chemodynamic therapy of cancer is limited by insufficient endogenous H2O2 generation and acidity in the tumor microenvironment (TME). Herein, we developed a biodegradable theranostic platform (pLMOFePt-TGO) invol...

    Authors: Caiyun Zhang, Peng Wang, Ya’ nan Zhang, Pengpeng Lu, Xiaodan Huang, Yinfeng Wang, Lang Ran, Huan Xin, Xiaotong Xu, Wenjuan Gao, Yu Sun, Li Zhang and Guilong Zhang
    Citation: Journal of Nanobiotechnology 2023 21:59
  26. Over the past decade, a proliferation of research has used nanoparticles to deliver gaseous signaling molecules for medical purposes. The discovery and revelation of the role of gaseous signaling molecules hav...

    Authors: Jiaxuan Sun, Wenzhi Wang, Xianli Hu, Xianzuo Zhang, Chen Zhu, Jinming Hu and Ruixiang Ma
    Citation: Journal of Nanobiotechnology 2023 21:58
  27. Globally, millions of patients suffer from regenerative deficiencies, such as refractory wound healing, which is characterized by excessive inflammation and abnormal angiogenesis. Growth factors and stem cells...

    Authors: Jieqiong Cao, Yibo Zhang, Yiqi Yang, Junye Xie, Zijian Su, Fu Li, Jingsheng Li, Bihui Zhang, Zhenyu Wang, Peiguang Zhang, Zhixin Li, Liu He, Hongwei Liu, Wenjie Zheng, Shuixing Zhang, An Hong…
    Citation: Journal of Nanobiotechnology 2023 21:57
  28. Locoregional delivery of chimeric antigen receptor (CAR)-modified T (CAR-T) cells has emerged as a promising strategy for brain tumors. However, the complicated ex vivo cell manufacturing procedures and the ra...

    Authors: Lin Gao, Chongdeng Shi, Zhenmei Yang, Weiqiang Jing, Maosen Han, Jing Zhang, Cai Zhang, Chunwei Tang, Yuanmin Dong, Ying Liu, Chen Chen and Xinyi Jiang
    Citation: Journal of Nanobiotechnology 2023 21:56
  29. Acne is a chronic skin condition that has serious consequences for mental and social well-being because it frequently occurs on the face. Several acne treatment approaches have commonly been used but have been...

    Authors: Zijian Su, Yibo Zhang, Jieqiong Cao, Yuanmeng Sun, Yuling Cai, Bihui Zhang, Liu He, Zilei Zhang, Junye Xie, Qilin Meng, Lin Luo, Fu Li, Jingsheng Li, Jinting Zhang, Xiaojia Chen and An Hong
    Citation: Journal of Nanobiotechnology 2023 21:55

    The Correction to this article has been published in Journal of Nanobiotechnology 2024 22:70

  30. In the clinical course of Alzheimer’s disease (AD) development, the dementia phase is commonly preceded by a prodromal AD phase, which is mainly characterized by reaching the highest levels of Aβ and p-tau-med...

    Authors: Amanda Cano, Ester Esteban-de-Antonio, Mireia Bernuz, Raquel Puerta, Pablo García-González, Itziar de Rojas, Claudia Olivé, Alba Pérez-Cordón, Laura Montrreal, Raúl Núñez-Llaves, Óscar Sotolongo-Grau, Emilio Alarcón-Martín, Sergi Valero, Montserrat Alegret, Elvira Martín, Pamela V. Martino-Adami…
    Citation: Journal of Nanobiotechnology 2023 21:54
  31. Vulvovaginal candidiasis (VVC) is a mucosal infection of the female lower genital tract for which treatment using conventional antifungal drugs shows limited effectiveness. Herein, amphotericin B-loaded poly(l...

    Authors: Min Yang, Yuchao Cao, Zhifei Zhang, Jiajun Guo, Can Hu, Zhibiao Wang and Yonghong Du
    Citation: Journal of Nanobiotechnology 2023 21:53
  32. Inflammatory depression is closely related to neuroinflammation. However, current anti-inflammatory drugs have low permeability to cross blood–brain barrier with difficulties reaching the central nervous syste...

    Authors: Ting-ting Zhu, He Wang, Han-wen Gu, Ling-sha Ju, Xin-miao Wu, Wei-tong Pan, Ming-ming Zhao, Jian-jun Yang and Pan-miao Liu
    Citation: Journal of Nanobiotechnology 2023 21:52
  33. Renal excretion is one of the major routes of nanomaterial elimination from the body. Many previous studies have found that graphene oxide nanosheets are excreted in bulk through the kidneys. However, how the ...

    Authors: Wei Chen, Bing Wang, Shanshan Liang, Meng Wang, Lingna Zheng, Si Xu, Jiali Wang, Hao Fang, Pu Yang and Weiyue Feng
    Citation: Journal of Nanobiotechnology 2023 21:51
  34. Postoperative pain (POP) can promote tumor recurrence and reduce the cancer patient's quality of life. However, POP management has always been separated from tumor treatment in clinical practice, and tradition...

    Authors: Mingxu Zhao, Shasha Zhu, Ding Zhang, Chang Zhou, Zhilai Yang, Chunhui Wang, Xuesheng Liu and Jiqian Zhang
    Citation: Journal of Nanobiotechnology 2023 21:50
  35. Aggregation-induced emission luminogens (AIEgens) have emerged as novel phototherapeutic agents with high photostability and excellent performance to induce photodynamic and/or photothermal effects. In this st...

    Authors: Yinshan Lin, Mengmeng Yi, Xiaoling Guan, Enen Chen, Langyu Yang, Songpei Li, Ying Li and Lingmin Zhang
    Citation: Journal of Nanobiotechnology 2023 21:49
  36. In clinical practice, cisplatin is the most commonly used chemotherapy drug to treat a range of malignancies. Severe ROS-regulated nephrotoxicity, however, restricts its applicability. Currently, the main mech...

    Authors: Chaofan Liu, Sajin Zhou, Haoqiang Lai, Lei Shi, Weibin Bai and Xiaoling Li
    Citation: Journal of Nanobiotechnology 2023 21:47
  37. The coalition of DNA nanotechnology with diversiform inorganic nanoparticles offers powerful tools for the design and construction of stimuli-responsive drug delivery systems with spatiotemporal controllabilit...

    Authors: Yuanhuan Yang, Xueting Cai, Menglin Shi, Xiaobo Zhang, Yang Pan, Yue Zhang, Huangxian Ju and Peng Cao
    Citation: Journal of Nanobiotechnology 2023 21:46
  38. Although temozolomide (TMZ) provides significant clinical benefit for glioblastoma (GBM), responses are limited by the emergence of acquired resistance. Here, we demonstrate that exosomal circCABIN1 secreted f...

    Authors: Xiao Liu, Qingdong Guo, Guangxun Gao, Zhengcong Cao, Zhihao Guan, Bo Jia, Weizhong Wang, Kuo Zhang, Wangqian Zhang, Shuning Wang, Weina Li, Qiang Hao, Yingqi Zhang, Meng Li, Wei Zhang and Jintao Gu
    Citation: Journal of Nanobiotechnology 2023 21:45
  39. Photoreceptor degeneration is one of the major causes of progressive blindness which lacks of curative treatment. GW2580, a highly selective inhibitor of colony-stimulating factor 1 receptor, has the protectiv...

    Authors: Peipei Cao, Yue Cheng, Zhi Li, Ya-Jia Cheng, Xiaoqi Chu, Chao Geng, Xuebo Yin and Yuhao Li
    Citation: Journal of Nanobiotechnology 2023 21:44
  40. Intracellular drug delivery is at the heart of many diagnosis procedures and a key step in gene therapy. Research has been conducted to bypass cell barriers for controlled intracellular drug release and made c...

    Authors: Majid Layachi, Anthony Treizebré, Laurent Hay, David Gilbert, Jean Pesez, Quentin D’Acremont, Kevin Braeckmans, Quentin Thommen and Emmanuel Courtade
    Citation: Journal of Nanobiotechnology 2023 21:43
  41. The process of transcatheter arterial chemoembolization is characterized by the ability to accurately deliver chemotherapy drugs with minimal systemic side effects and has become the standard treatment for unr...

    Authors: Sitong Wu, Kevin Fan, Qi Yang, Zhao Chen, Yi Hou, Yinghua Zou, Weibo Cai and Lei Kang
    Citation: Journal of Nanobiotechnology 2023 21:42
  42. Clinically, activated EGFR mutation associated chemo-drugs resistance has severely threaten NSCLC patients. Nanoparticle based small interfering RNA (siRNA) therapy representing another promising alternative b...

    Authors: Haoying Huang, Xiaohan Yi, Qingyun Wei, Mengyuan Li, Xueting Cai, Yan Lv, Ling Weng, Yujie Mao, Weiwei Fan, Mengmeng Zhao, Zhongpei Weng, Qing Zhao, Kewei Zhao, Meng Cao, Jing Chen and Peng Cao
    Citation: Journal of Nanobiotechnology 2023 21:41
  43. Cancer immunotherapy shows promising potential for treating breast cancer. While patients may have heterogeneous treatment responses for adjuvant therapy, it is challenging to predict an individual patient’s r...

    Authors: Zhuhao Wu, Zheng Ao, Hongwei Cai, Xiang Li, Bin Chen, Honglei Tu, Yijie Wang, Rongze Olivia Lu, Mingxia Gu, Liang Cheng, Xin Lu and Feng Guo
    Citation: Journal of Nanobiotechnology 2023 21:40
  44. The adoption of pulmonary vaccines to advantageously provide superior local mucosal protection against aerosolized pathogens has been faced with numerous logistical and practical challenges. One of these persi...

    Authors: Zachary S. Stillman, Gerald E. Decker, Michael R. Dworzak, Eric D. Bloch and Catherine A. Fromen
    Citation: Journal of Nanobiotechnology 2023 21:39
  45. Wound repair, along with skin appendage regeneration, is challenged by insufficient angiogenesis and neural regeneration. Therefore, promoting both proangiogenic and neuro-regenerative therapeutic effects is e...

    Authors: Tiejun Yuan, Minhong Tan, Yang Xu, Qiyao Xiao, Hui Wang, Chen Wu, Fulun Li and Lihua Peng
    Citation: Journal of Nanobiotechnology 2023 21:38
  46. Cancer stem cells (CSCs) are crucial for the growth, metastasis, drug resistance, recurrence, and spread of tumors. Napabucasin (NAP) could effectively inhibit CSC, but its mechanism has not been fully explain...

    Authors: Boping Jing, Feng Guo, Rui An, Yu Gao, Yuman Li, Yuji Xie, Jing Wang, Yihan Chen, He Li, Tang Gao, Qiaofeng Jin, Li Zhang and Mingxing Xie
    Citation: Journal of Nanobiotechnology 2023 21:37
  47. Although a large amount of evidence has revealed that amyloid β (Aβ), especially Aβ oligomers, protofibrils, and pyroglutamated Aβs, participate primarily in the pathophysiological processes of Alzheimer’s dis...

    Authors: Akiko Amano, Nobuo Sanjo, Wataru Araki, Yasutaka Anraku, Makoto Nakakido, Etsuro Matsubara, Takami Tomiyama, Tetsuya Nagata, Kouhei Tsumoto, Kazunori Kataoka and Takanori Yokota
    Citation: Journal of Nanobiotechnology 2023 21:36

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