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  1. Inspired by nature, green chemistry uses various biomolecules, such as proteins, as reducing agents to synthesize metallic nanostructures. This methodology provides an alternative route to conventional harsh s...

    Authors: Roman Nudelman, Hashim Alhmoud, Bahman Delalat, Ishdeep Kaur, Anastasia Vitkin, Laure Bourgeois, Ilan Goldfarb, Anna Cifuentes-Rius, Nicolas H. Voelcker and Shachar Richter
    Citation: Journal of Nanobiotechnology 2022 20:482
  2. Currently available anti-leukemia drugs have shown limited success in the treatment of acute myeloid leukemia (AML) due to their poor access to bone marrow niche supporting leukemic cell proliferation.

    Authors: Ki Hyun Bae, Fritz Lai, Jamie Mong, Akiko Niibori-Nambu, Kiat Hwa Chan, Zhisheng Her, Motomi Osato, Min-Han Tan, Qingfeng Chen and Motoichi Kurisawa
    Citation: Journal of Nanobiotechnology 2022 20:481
  3. Precision medicine is the ultimate goal for current disease therapies, including tumor and infection. The lack of specific targeted drugs for liver cancer and the lack of specific anti-infective drugs in the t...

    Authors: Yiyin Zhang, Yiling Li, Qiming Xia, Yirun Li, Shengxi Jin, Qijiang Mao, Chao Liu, Xiaoxiao Fan and Hui Lin
    Citation: Journal of Nanobiotechnology 2022 20:480
  4. Accumulating evidence suggests that osteoclastogenesis and angiogenesis in subchondral bone are critical destructive factors in the initiation and progression of osteoarthritis (OA). Herein, methoxypolyethylen...

    Authors: Zhikai Wu, Kai Yuan, Qian Zhang, Jiong Jiong Guo, Huilin Yang and Feng Zhou
    Citation: Journal of Nanobiotechnology 2022 20:479
  5. Swine influenza A viruses (SwIAVs) pose an economic and pandemic threat, and development of novel effective vaccines is of critical significance. We evaluated the performance of split swine influenza A virus (...

    Authors: V. Patil, J. F. Hernandez-Franco, G. Yadagiri, D. Bugybayeva, S. Dolatyabi, N. Feliciano-Ruiz, J. Schrock, J. Hanson, J. Ngunjiri, H. HogenEsch and G. J. Renukaradhya
    Citation: Journal of Nanobiotechnology 2022 20:477

    The Correction to this article has been published in Journal of Nanobiotechnology 2022 20:539

  6. Multidrug resistance (MDR) has been restricting the efficacy of chemotherapy, which mainly include pump resistance and non-pump resistance. In order to fight overall MDR, a novel targeted gene/drug co-deliver ...

    Authors: Changduo Wang, Zhipeng Li, Ping Xu, Lisa Xu, Shangcong Han and Yong Sun
    Citation: Journal of Nanobiotechnology 2022 20:476
  7. Phototherapy is a conducive and non-invasive strategy for cancer therapy under light irradiation. Inspiringly, fluorescence imaging in the second near-infrared window (NIR-II, 1000–1700 nm) holds a great promi...

    Authors: Sha Yang, Gui-long Wu, Na Li, Minghui Wang, Peixian Wu, Yuxuan He, Wei Zhou, Hao Xiao, Xiaofeng Tan, Li Tang and Qinglai Yang
    Citation: Journal of Nanobiotechnology 2022 20:475
  8. Chronic metabolic diseases such as diabetes are characterized by delayed wound healing and a dysregulation of the inflammatory phase of wound repair. Our study focuses on changes in the payload of extracellula...

    Authors: Dong Jun Park, Erika Duggan, Kayla Ho, Robert A. Dorschner, Marek Dobke, John P. Nolan and Brian P. Eliceiri
    Citation: Journal of Nanobiotechnology 2022 20:474
  9. Platinum nanoparticles have been demonstrated to have excellent anticancer properties. However, because of the lack of specificity they must be delivered to the tumor in amounts sufficient to reach the desired...

    Authors: María Sancho-Albero, Ana Martín-Pardillos, Lluís Lujan, Víctor Sebastian, Jesús Santamaria and Pilar Martín-Duque
    Citation: Journal of Nanobiotechnology 2022 20:473
  10. Metastasis and chemical resistance are the most serious problems in the treatment of highly aggressive uveal melanoma (UM). The newly identified lncRNA OUM1 is overexpressed in UM, functions as a catalyst and reg...

    Authors: Yue Li, Fang Li, Hui Pan, Xiaolin Huang, Jie Yu, Xueru Liu, Qinghao Zhang, Caiwen Xiao, He Zhang and Leilei Zhang
    Citation: Journal of Nanobiotechnology 2022 20:472
  11. Ovarian cancer is a highly fatal gynecologic malignancy worldwide. Chemotherapy remains the primary modality both for primary and maintenance treatments of ovarian cancer. However, the progress in developing c...

    Authors: Guang Li, Mingjian Ling, Kunyi Yu, Wei Yang, Qiwen Liu, Lijuan He, Xuzi Cai, Min Zhong, Ziyi Mai, Rui Sun, Yuanling Xiao, Zhiqiang Yu and Xuefeng Wang
    Citation: Journal of Nanobiotechnology 2022 20:471
  12. Pathogenic dental plaque biofilms are universal and harmful, which can result in oral infections and systemic diseases. Many conventional therapeutic methods have proven insufficient or ineffective against pla...

    Authors: Yangheng Zhang, Rixin Chen, Yuxian Wang, Peng Wang, Jiajie Pu, Xiaoqiang Xu, Faming Chen, Ling Jiang, Qing Jiang and Fuhua Yan
    Citation: Journal of Nanobiotechnology 2022 20:470
  13. Osteoarthritis (OA) is a common joint disorder worldwide which causes great health and economic burden. However, there remains an unmet goal to develop an effective therapeutic method to prevent or delay OA. C...

    Authors: Yu Jin, Qing Zhang, Xing Qin, Zhen Liu, Zhenxia Li, Xiaoxia Zhong, Lunguo Xia, Jie He and Bing Fang
    Citation: Journal of Nanobiotechnology 2022 20:469
  14. The hypoimmunogenicity of tumors is one of the main bottlenecks of cancer immunotherapy. Enhancing tumor immunogenicity can improve the efficacy of tumor immunotherapy by increasing antigen exposure and presen...

    Authors: Xiaowen Zhong, Chenyang Li, Guangzong Zhao, Mengmeng Li, Shuning Chen, Yang Cao, Qi Wang, Jiangchuan Sun, Shenyin Zhu and Shufang Chang
    Citation: Journal of Nanobiotechnology 2022 20:468
  15. In 2020, nearly 20 million peoples got cancer and nearly 10 million peoples died of cancer, indicating the cancer remains a great threat to human health and life. New therapies are still in urgent demand. We h...

    Authors: Tao Luo, Yile Wang and Jinke Wang
    Citation: Journal of Nanobiotechnology 2022 20:467
  16. Tumor phototheranostics holds a great promise on account of its high spatiotemporal resolution, tumor-specificity, and noninvasiveness. However, physical limitation of light penetration and “always on” propert...

    Authors: Chaoyi Chen, Yuwen Chen, Lulu Zhang, Xuanhao Wang, Qingshuang Tang, Yan Luo, Yuan Wang, Cheng Ma and Xiaolong Liang
    Citation: Journal of Nanobiotechnology 2022 20:466
  17. Tissue engineering of hair follicles (HFs) has enormous potential for hair loss treatment. However, certain challenges remain, including weakening of the dermal papilla cell (DPC) viability, proliferation, and...

    Authors: Yufan Zhang, Panjing Yin, Junfei Huang, Lunan Yang, Zhen Liu, Danlan Fu, Zhiqi Hu, Wenhua Huang and Yong Miao
    Citation: Journal of Nanobiotechnology 2022 20:465
  18. Glucocorticoids (GCs) overuse is associated with decreased bone mass and osseous vasculature destruction, leading to severe osteoporosis. Platelet lysates (PL) as a pool of growth factors (GFs) were widely use...

    Authors: Gang Zheng, Hai-Wei Ma, Guang-Heng Xiang, Gao-Lu He, Han-Chen Cai, Zi-Han Dai, Yan-Lin Chen, Yan Lin, Hua-Zi Xu, Wen-Fei Ni, Cong Xu, Hai-Xiao Liu and Xiang-Yang Wang
    Citation: Journal of Nanobiotechnology 2022 20:220
  19. In the field of nanoscience there is an increasing interest to follow dynamics of nanoparticles (NP) in cells with an emphasis on endo-lysosomal pathways and long-term NP fate. During our research on this topi...

    Authors: Aura Maria Moreno-Echeverri, Eva Susnik, Dimitri Vanhecke, Patricia Taladriz-Blanco, Sandor Balog, Alke Petri-Fink and Barbara Rothen-Rutishauser
    Citation: Journal of Nanobiotechnology 2022 20:464
  20. Exosome mediated mRNA delivery is a promising strategy for the treatment of multiple diseases. However, the low yield of exosomes is a bottleneck for clinical translation. In this study, we boosted exosome pro...

    Authors: Rongxin Zhang, Te Bu, Ruidan Cao, Zhelong Li, Chen Wang, Bing Huang, Mengying Wei, Lijun Yuan and Guodong Yang
    Citation: Journal of Nanobiotechnology 2022 20:463
  21. Osteoporosis (OP) is characterized by a loss in bone mass and mineral density. The stimulation of the canonical Wnt/β-catenin pathway has been reported to promote bone formation, this pathway is controlled by ...

    Authors: Patricia García-García, Ricardo Reyes, Daniel García-Sánchez, Flor María Pérez-Campo, José Carlos Rodríguez-Rey, Carmen Évora, Patricia Díaz-Rodríguez and Araceli Delgado
    Citation: Journal of Nanobiotechnology 2022 20:462
  22. Traumatic peripheral nerve injury (TPNI) is a major medical problem with no universally accepted pharmacologic treatment. We hypothesized that encapsulation of pro-angiogenic erythropoietin (EPO) in amphiphili...

    Authors: Kristen M. Manto, Prem Kumar Govindappa, Brandon Martinazzi, Aijie Han, John P. Hegarty, Zachary Koroneos, M. A. Hassan Talukder and John C. Elfar
    Citation: Journal of Nanobiotechnology 2022 20:461
  23. Repair of spinal cord injury (SCI) depends on microenvironment improvement and the reconnection between injured axons and regenerated neurons. Here, we fabricate a GelMA-MXene hydrogel nerve conduit with elect...

    Authors: Jiaying Cai, Hui Zhang, Yangnan Hu, Zhichun Huang, Yan Wang, Yu Xia, Xiaoyan Chen, Jiamin Guo, Hong Cheng, Lin Xia, Weicheng Lu, Chen Zhang, Jingdun Xie, Huan Wang and Renjie Chai
    Citation: Journal of Nanobiotechnology 2022 20:460
  24. Exfoliation syndrome presents as an accumulation of insoluble fibrillar aggregates that commonly correlates with age and causes ocular complications, most notably open-angle glaucoma. Despite advances in under...

    Authors: Mehdi Ghaffari Sharaf, Kosala D. Waduthanthri, Andrew Crichton, Karim F. Damji and Larry D. Unsworth
    Citation: Journal of Nanobiotechnology 2022 20:459
  25. Due to the urgent demand for more anti-cancer methods, the new applications of metal ions in cancer have attracted increasing attention. Especially the three kinds of the new mode of cell death, including ferr...

    Authors: Han Hu, Qi Xu, Zhimin Mo, Xiaoxi Hu, Qianyuan He, Zhanjie Zhang and Zushun Xu
    Citation: Journal of Nanobiotechnology 2022 20:457
  26. MicroRNAs (miRNAs) are small non-coding RNAs with ~ 22 nucleotides, playing important roles in the post-transcriptional regulation of gene expression. The expression profiles of many miRNAs are closely related...

    Authors: Ying Gan, Mingxing Zhou, Huiqiang Ma, Jiameng Gong, Shan-Yu Fung, Xian Huang and Hong Yang
    Citation: Journal of Nanobiotechnology 2022 20:456
  27. Phellinus linteus (PL), which is a typical medicinal fungus, has been shown to have antitumor and anti-inflammatory activities. However, studies on the effect of anti-photoaging are limited. Studies have shown th...

    Authors: Jingxia Han, Ting Wu, Jing Jin, Zhiyang Li, Wenjun Cheng, Xintong Dai, Kai Yang, Heng Zhang, Zhiyuan Zhang, Haohao Zhang, Rong Fan, Shaoting Zheng, Haoyang Liu, Yinan Li, Huan Zhao, Cheng Yao…
    Citation: Journal of Nanobiotechnology 2022 20:455
  28. Resolvin D1 (RvD1) has been shown to provide effective protection against ischemia–reperfusion injury in multiple vital organs such as the heart, brain, kidney. However, the clinical translational potential of...

    Authors: Xueyi Weng, Haipeng Tan, Zheyong Huang, Jing Chen, Ning Zhang, Qiaozi Wang, Qiyu Li, Jinfeng Gao, Dili Sun, Wusiman Yakufu, Zhengmin Wang, Weiyan Li, Guangrui Zhu, Zhiqing Pang, Yanan Song, Juying Qian…
    Citation: Journal of Nanobiotechnology 2022 20:454
  29. Pancreatic cancer remains among the most prevalent and aggressive forms of cancer. While immunotherapeutic treatment strategies have shown some promise in affected patients, the benefits of these interventions...

    Authors: Libin Chen, Wang Xue, Jing Cao, Shengmin Zhang, Yiqing Zeng, Ling Ma, Xuechen Qian, Qing Wen, Yurong Hong, Zhan Shi and Youfeng Xu
    Citation: Journal of Nanobiotechnology 2022 20:453
  30. Ossification of the posterior longitudinal ligament (OPLL) is a disabling disease whose pathogenesis is still unclear, and there are no effective cures or prevention methods. Exosomal miRNA plays an important ...

    Authors: Yifan Tang, Yanqing Sun, Junkai Zeng, Bo Yuan, Yin Zhao, Xiangwu Geng, Lianshun Jia, Shengyuan Zhou and Xiongsheng Chen
    Citation: Journal of Nanobiotechnology 2022 20:452
  31. Mesenchymal stem cells (MSC) secrete extracellular vesicles (EV) with a regenerative profile, and an increasing number of studies have focused on the utilization of MSC-EV for therapeutic drug delivery. Howeve...

    Authors: Kyong-Su Park, Markus Bergqvist, Cecilia Lässer and Jan Lötvall
    Citation: Journal of Nanobiotechnology 2022 20:451
  32. Advances in diagnostic imaging have provided unprecedented opportunities to detect diseases at early stages and with high reliability. Diagnostic imaging is also crucial to monitoring the progress or remission...

    Authors: Ahmed Refaat, May Lin Yap, Geoffrey Pietersz, Aidan Patrick Garing Walsh, Johannes Zeller, Blanca del Rosal, Xiaowei Wang and Karlheinz Peter
    Citation: Journal of Nanobiotechnology 2022 20:450
  33. In the frame of radiotherapy treatment of cancer, radioresistance remains a major issue that still needs solutions to be overcome. To effectively improve the radiosensitivity of tumors and reduce the damage of...

    Authors: Hao Sun, Hui Cai, Chang Xu, Hezheng Zhai, François Lux, Yi Xie, Li Feng, Liqing Du, Yang Liu, Xiaohui Sun, Qin Wang, Huijuan Song, Ningning He, Manman Zhang, Kaihua Ji, Jinhan Wang…
    Citation: Journal of Nanobiotechnology 2022 20:449
  34. Reactive oxygen species (ROS) at supraphysiological concentration have a determinate role in contributing to immuno-metabolic disorders in the epithelial immune microenvironment (EIME) of psoriatic lesions. Wi...

    Authors: Jiangmei Xu, Hao Chen, Haisheng Qian, Fei Wang and Yunsheng Xu
    Citation: Journal of Nanobiotechnology 2022 20:448
  35. In oral and maxillofacial surgery, flap repair is essential to the quality of postoperative life. Still, thrombosis is fatal for the survival of the flaps. Besides, some postoperative thrombotic diseases, such...

    Authors: Zichen Cao, Xinyu Zhang, Zheng Wei, Chuanhui Song, Huihui Zou, Jianchuan Ran, Hongbo Zhang, Diya Xie, Shengwei Han, Yufeng Wang, Yu Cai and Wei Han
    Citation: Journal of Nanobiotechnology 2022 20:447
  36. Pancreatic ductal adenocarcinoma (PDAC) is one of the most fatal cancers worldwide with high mortality, which is mainly due to the lack of reliable biomarkers for PDAC diagnosis/prognosis in the early stages a...

    Authors: Wei Zhang, Douglas H. Campbell, Bradley J. Walsh, Nicolle H. Packer, Dingbin Liu and Yuling Wang
    Citation: Journal of Nanobiotechnology 2022 20:446
  37. Pseudomonas aeruginosa infection is a severe acute suppurative ulcer that engulfs virtually the entire tissue in a short period and leads to devastating destruction. Antibiotic therapy is a common approach for th...

    Authors: Hongwei Wang, Fangying Song, Jing Feng, Xia Qi, Li Ma, Lixin Xie, Weiyun Shi and Qingjun Zhou
    Citation: Journal of Nanobiotechnology 2022 20:445
  38. Tissue engineering scaffolds are essential for repairing bone defects. The use of biomimetic scaffolds for bone tissue engineering has been investigated for decades. To date, the trend in this area has been mo...

    Authors: Yangyufan Wang, Bin Kong, Xiang Chen, Rui Liu, Yuanjin Zhao, Zhuxiao Gu and Qing Jiang
    Citation: Journal of Nanobiotechnology 2022 20:444
  39. The formation of biomolecular condensates via liquid‒liquid phase separation (LLPS) is an advantageous strategy for cells to organize their subcellular compartments for diverse functions. Recent findings sugge...

    Authors: Zhen Xing, Jing Xue, Xindian Ma, Congwei Han, Zhenzhen Wang, Shunhuang Luo, Chunming Wang, Lei Dong and Junfeng Zhang
    Citation: Journal of Nanobiotechnology 2022 20:442
  40. Despite being a promising strategy, current chemotherapy for gastric cancer (GC) is limited due to adverse side effects and poor survival rates. Therefore, new drug-delivery platforms with good biocompatibilit...

    Authors: Rongbo Wang, Keum-yun Ha, Sanjeevram Dhandapani and Yeon-Ju Kim
    Citation: Journal of Nanobiotechnology 2022 20:441
  41. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) led to COVID-19 and has become a pandemic worldwide with mortality of millions. Nanotechnology can be used to deliver antiviral medicines or other t...

    Authors: Saman Yasamineh, Hesam Ghafouri Kalajahi, Pooneh Yasamineh, Yalda Yazdani, Omid Gholizadeh, Raheleh Tabatabaie, Hamed Afkhami, Fatemeh Davodabadi, Alireza Khanalipour farkhad, Daryoush Pahlevan, Akram Firouzi-Amandi, Kazem Nejati-Koshki and Mehdi Dadashpour
    Citation: Journal of Nanobiotechnology 2022 20:440
  42. Dysbiosis or imbalance of gut microbiota in Alzheimer's disease (AD) affects the production of short-chain fatty acids (SCFAs), whereas exogenous SCFAs supplementation exacerbates brain Aβ burden in APP/PS1 mi...

    Authors: Ni Liu, Changwen Yang, Xiaohan Liang, Kai Cao, Jun Xie, Qingming Luo and Haiming Luo
    Citation: Journal of Nanobiotechnology 2022 20:439
  43. Clinical diagnostics rely heavily on the detection and quantification of cancer biomarkers. The rapid detection of cancer-specific biomarkers is of great importance in the early diagnosis of cancers and plays ...

    Authors: Hossein Kamali, Shiva Golmohammadzadeh, Hamed Zare, Rahim Nosrati, Mohammad Fereidouni and Hossein Safarpour
    Citation: Journal of Nanobiotechnology 2022 20:438
  44. Photodynamic therapy (PDT), and sonodynamic therapy (SDT) that developed from PDT, have been studied for decades to treat solid tumors. Compared with other deep tumors, the accessibility of urological tumors (...

    Authors: Xiao Hu, Yu-Sen Zhang, Yi-Chao Liu, Na Wang, Xian-Tao Zeng and Ling-Ling Zhang
    Citation: Journal of Nanobiotechnology 2022 20:437
  45. Nanomedicine has emerged as a promising strategy for cancer treatment. The most representative nanomedicine used in clinic is PEGylated liposomal doxorubicin DOXIL®, which is first FDA-approved nanomedicine. Howe...

    Authors: Man Kyu Shim, Suah Yang, Jooho Park, Jun Sik Yoon, Jinseong Kim, Yujeong Moon, Nayeon Shim, Mihee Jo, Yongwhan Choi and Kwangmeyung Kim
    Citation: Journal of Nanobiotechnology 2022 20:436
  46. Exosomes of human cardiosphere-derived cells (CDCs) are very promising for treating cardiovascular disorders. However, the current challenge is inconvenient delivery methods of exosomes for clinical applicatio...

    Authors: Liang Mao, Yun-Da Li, Ruo-Lan Chen, Gang Li, Xiao-Xia Zhou, Fei Song, Chan Wu, Yu Hu, Yi-Xiang Hong, Xitong Dang, Gui-Rong Li and Yan Wang
    Citation: Journal of Nanobiotechnology 2022 20:435
  47. The incidence of myocardial ischaemia‒reperfusion injury (MIRI) is increasing every year, and there is an urgent need to develop new therapeutic approaches. Nrf2 is thought to play a protective role during MIR...

    Authors: Tianyi Wang, Tingting Zhou, Mingming Xu, Shuo Wang, Anqi Wu, Mingyang Zhang, You Lang Zhou and Jiahai Shi
    Citation: Journal of Nanobiotechnology 2022 20:434

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