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  1. Various obstacles are encountered by mammalian spermatozoa during their journey through the female genital tract, and only few or none will reach the site of fertilization. Currently, there are limited technic...

    Authors: Jean M Feugang, Ramey C Youngblood, Jonathan M Greene, Abed S Fahad, William A Monroe, Scott T Willard and Peter L Ryan

    Citation: Journal of Nanobiotechnology 2012 10:45

    Content type: Research

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  2. Particulates incorporating DNA are promising vehicles for gene delivery, with the ability to protect DNA and provide for controlled, localized, and sustained release and transfection. Zein, a hydrophobic prote...

    Authors: Mary C Regier, Jessica D Taylor, Tyler Borcyk, Yiqi Yang and Angela K Pannier

    Citation: Journal of Nanobiotechnology 2012 10:44

    Content type: Research

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  3. Silver nanoparticles (AgNps) have attracted much interest in biomedical engineering, since they have excellent antimicrobial properties. Therefore, AgNps have often been considered for incorporation into medic...

    Authors: Carolina Alves dos Santos, Angela Faustino Jozala, Adalberto Pessoa Jr and Marcelo Martins Seckler

    Citation: Journal of Nanobiotechnology 2012 10:43

    Content type: Research

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  4. English ivy (Hedera helix) is well known for its adhesive properties and climbing ability. Essential to its ability to adhere to vertical surfaces is the secretion of a nanocomposite adhesive containing spherical...

    Authors: Jason N Burris, Scott C Lenaghan, Mingjun Zhang and C Neal Stewart

    Citation: Journal of Nanobiotechnology 2012 10:41

    Content type: Short Communication

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  5. Nanoparticles (NPs) are currently used in a wide variety of fields such as technology, medicine and industry. Due to the novelty of these applications and to ensure their success, a precise characterization of...

    Authors: Juan A Varela, Mariana G Bexiga, Christoffer Åberg, Jeremy C Simpson and Kenneth A Dawson

    Citation: Journal of Nanobiotechnology 2012 10:39

    Content type: Short Communication

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  6. Nanoparticle based delivery of anticancer drugs have been widely investigated. However, a very important process for Research & Development in any pharmaceutical industry is scaling nanoparticle formulation te...

    Authors: Amalendu P Ranjan, Anindita Mukerjee, Lawrence Helson and Jamboor K Vishwanatha

    Citation: Journal of Nanobiotechnology 2012 10:38

    Content type: Research

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  7. Inflammation plays an important role in many pathologies, including cardiovascular diseases, neurological conditions and oncology, and is considered an important predictor for disease progression and outcome. In ...

    Authors: Tessa Geelen, Sin Yuin Yeo, Leonie EM Paulis, Lucas WE Starmans, Klaas Nicolay and Gustav J Strijkers

    Citation: Journal of Nanobiotechnology 2012 10:37

    Content type: Research

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  8. Intrinsically fluorescent glucose derived carbon nanospheres (CSP) efficiently enter mammalian cells and also cross the blood brain barrier (BBB). However, the mechanistic details of CSP entry inside mammalian...

    Authors: Ruthrotha B Selvi, Snehajyoti Chatterjee, Dinesh Jagadeesan, Piyush Chaturbedy, Bangalore Srinivas Suma, Muthusamy Eswaramoorthy and Tapas K Kundu

    Citation: Journal of Nanobiotechnology 2012 10:35

    Content type: Research

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  9. The application of nanotechnology in biology and medicine represents a significant paradigm shift in the approach to the treatment of cancer. Evidence suggests that when exposed to near-infrared radiation (NIR...

    Authors: Aaron Tan, Seyed Yazdan Madani, Jayakumar Rajadas, Giorgia Pastorin and Alexander M Seifalian

    Citation: Journal of Nanobiotechnology 2012 10:34

    Content type: Research

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  10. Superparamagnetic nanoparticles (MNPs) have been progressively explored for their potential in biomedical applications and in particular as a contrast agent for diagnostic imaging, for magnetic drug delivery a...

    Authors: Silvia Panseri, Carla Cunha, Teresa D’Alessandro, Monica Sandri, Gianluca Giavaresi, Maurilio Marcacci, Clark T Hung and Anna Tampieri

    Citation: Journal of Nanobiotechnology 2012 10:32

    Content type: Research

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  11. Nanobiotechnology is the application of nanotechnology in biological fields. Nanotechnology is a multidisciplinary field that currently recruits approach, technology and facility available in conventional as w...

    Authors: Md Fakruddin, Zakir Hossain and Hafsa Afroz

    Citation: Journal of Nanobiotechnology 2012 10:31

    Content type: Review

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    The Retraction Note to this article has been published in Journal of Nanobiotechnology 2012 10:40

  12. Dengue is a global public health problem for which no drug or vaccine is available. Currently, there is increasing interest in developing non-replicating dengue vaccines based on a discrete antigenic domain of...

    Authors: Upasana Arora, Poornima Tyagi, Sathyamangalam Swaminathan and Navin Khanna

    Citation: Journal of Nanobiotechnology 2012 10:30

    Content type: Short Communication

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  13. Time-resolved quantitative colocalization analysis is a method based on confocal fluorescence microscopy allowing for a sophisticated characterization of nanomaterials with respect to their intracellular traff...

    Authors: Christoph Schweiger, Raimo Hartmann, Feng Zhang, Wolfgang J Parak, Thomas H Kissel and Pilar Rivera_Gil

    Citation: Journal of Nanobiotechnology 2012 10:28

    Content type: Research

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  14. Iron oxide nanoparticles (IONPs) have increasing applications in biomedicine, however fears over long term stability of polymer coated particles have arisen. Gold coating IONPs results in particles of increase...

    Authors: Clare Hoskins, Yue Min, Mariana Gueorguieva, Craig McDougall, Alexander Volovick, Paul Prentice, Zhigang Wang, Andreas Melzer, Alfred Cuschieri and Lijun Wang

    Citation: Journal of Nanobiotechnology 2012 10:27

    Content type: Research

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  15. The upregulation of intercellular adhesion molecule-1 (ICAM-1) on the endothelium of blood vessels in response to pro-inflammatory stimuli is of major importance for the regulation of local inflammation in car...

    Authors: Leonie EM Paulis, Igor Jacobs, Nynke M van den Akker, Tessa Geelen, Daniel G Molin, Lucas WE Starmans, Klaas Nicolay and Gustav J Strijkers

    Citation: Journal of Nanobiotechnology 2012 10:25

    Content type: Research

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  16. The interaction of a nanomaterial (NM) with a biological system depends not only on the size of its primary particles but also on the size, shape and surface topology of its aggregates and agglomerates. A meth...

    Authors: Pieter-Jan De Temmerman, Elke Van Doren, Eveline Verleysen, Yves Van der Stede, Michel Abi Daoud Francisco and Jan Mast

    Citation: Journal of Nanobiotechnology 2012 10:24

    Content type: Research

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  17. Electrospun nanofibers have been widely used as substrata for mammalian cell culture owing to their structural similarity to natural extracellular matrices. Structurally consistent electrospun nanofibers can b...

    Authors: Dongju Jung, Itsunari Minami, Sahishnu Patel, Jonghwan Lee, Bin Jiang, Qinghua Yuan, Liu Li, Sachiko Kobayashi, Yong Chen, Ki-Bum Lee and Norio Nakatsuji

    Citation: Journal of Nanobiotechnology 2012 10:23

    Content type: Research

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  18. Despite the availability of conventional devices for making single-cell manipulations, determining the hardness of a single cell remains difficult. Here, we consider the cell to be a linear elastic body and ap...

    Authors: Koichi Nakanishi, Akinori Kogure, Takenao Fujii, Ryohei Kokawa and Keiji Deuchi

    Citation: Journal of Nanobiotechnology 2012 10:22

    Content type: Research

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  19. One of the goals in the field of structural DNA nanotechnology is the use of DNA to build up 2- and 3-D nanostructures. The research in this field is motivated by the remarkable structural features of DNA as w...

    Authors: Elad D Mentovich, Konstantin Livanov, Deepak K Prusty, Mukules Sowwan and Shachar Richter

    Citation: Journal of Nanobiotechnology 2012 10:21

    Content type: Research

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  20. Alpha 1- antitrypsin (α1AT) belongs to the superfamily of serpins and inhibits different proteases. α1AT protects the lung from cellular inflammatory enzymes. In the absence of α1AT, the degradation of lung ti...

    Authors: Nazanin Pirooznia, Sadegh Hasannia, Abbas Sahebghadam Lotfi and Mostafa Ghanei

    Citation: Journal of Nanobiotechnology 2012 10:20

    Content type: Research

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  21. Diseases such as tuberculosis (TB) have always had a large impact on human health. Bacillus Calmette-Guérin (BCG) is used as a surrogate for TB during the development of anti-TB drugs. Nanoparticles (NPs) have...

    Authors: Yan Zhou, Ying Kong, Subrata Kundu, Jeffrey D Cirillo and Hong Liang

    Citation: Journal of Nanobiotechnology 2012 10:19

    Content type: Research

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  22. In the past decade spherical and rod-like viruses have been used for the design and synthesis of new kind of nanomaterials with unique chemical positioning, shape, and dimensions in the nanosize regime. Wild t...

    Authors: Jing C Zhou, Carissa M Soto, Mu-San Chen, Michael A Bruckman, Martin H Moore, Edward Barry, Banahalli R Ratna, Pehr E Pehrsson, Bradley R Spies and Tammie S Confer

    Citation: Journal of Nanobiotechnology 2012 10:18

    Content type: Research

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  23. Novel approaches for synthesis of gold nanoparticles (AuNPs) are of utmost importance owing to its immense applications in diverse fields including catalysis, optics, medical diagnostics and therapeutics. We r...

    Authors: Sougata Ghosh, Sumersing Patil, Mehul Ahire, Rohini Kitture, Deepanjali D Gurav, Amit M Jabgunde, Sangeeta Kale, Karishma Pardesi, Vaishali Shinde, Jayesh Bellare, Dilip D Dhavale and Balu A Chopade

    Citation: Journal of Nanobiotechnology 2012 10:17

    Content type: Research

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  24. Since silver-nanoparticles (NPs) possess an antibacterial activity, they were commonly used in medical products and devices, food storage materials, cosmetics, various health care products, and industrial prod...

    Authors: Liming Xu, Xuefei Li, Taro Takemura, Nobutaka Hanagata, Gang Wu and Laisheng Lee Chou

    Citation: Journal of Nanobiotechnology 2012 10:16

    Content type: Research

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  25. Iron oxide magnetic nanoparticles (MNP's) have an increasing number of biomedical applications. As such in vitro characterisation is essential to ensure the bio-safety of these particles. Little is known on th...

    Authors: Clare Hoskins, Alfred Cuschieri and Lijun Wang

    Citation: Journal of Nanobiotechnology 2012 10:15

    Content type: Research

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  26. To better understand the potential ecotoxicological impacts of silver nanoparticles released into freshwater environments, the Daphnia magna 48-hour immobilization test was used.

    Authors: Saba Asghari, Seyed Ali Johari, Ji Hyun Lee, Yong Seok Kim, Yong Bae Jeon, Hyun Jung Choi, Min Chaul Moon and Il Je Yu

    Citation: Journal of Nanobiotechnology 2012 10:14

    Content type: Research

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  27. Dengue is a major public health problem worldwide, especially in the tropical and subtropical regions of the world. Infection with a single Dengue virus (DENV) serotype causes a mild, self-limiting febrile illnes...

    Authors: Elisângela F Silva, Mariana Orsi, Ângela L Andrade, Rosana Z Domingues, Breno M Silva, Helena RC de Araújo, Paulo FP Pimenta, Michael S Diamond, Eliseu SO Rocha, Erna G Kroon, Luiz CC Malaquias and Luiz FL Coelho

    Citation: Journal of Nanobiotechnology 2012 10:13

    Content type: Short Communication

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  28. Nanogold has been investigated in a wide variety of biomedical applications because of the anti-inflammatory properties. The purpose of this study was to evaluate the effects of TPU (Therapeutic Pulsed Ultraso...

    Authors: Eduardo G Victor, Paulo CL Silveira, Jonathann C Possato, Guilherme L da Rosa, Uillian B Munari, Claudio T de Souza, Ricardo A Pinho, Luciano da Silva, Emilio L Streck and Marcos MS Paula

    Citation: Journal of Nanobiotechnology 2012 10:11

    Content type: Research

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  29. Angiogenesis is widely investigated in conjunction with cancer development, in particular because of the possibility of early stage detection and of new therapeutic strategies. However, such studies are negati...

    Authors: Chia-Chi Chien, Hsiang-Hsin Chen, Sheng-Feng Lai, Kang-Chao Wu, Xiaoqing Cai, Yeukuang Hwu, Cyril Petibois, Yong Chu and Giorgio Margaritondo

    Citation: Journal of Nanobiotechnology 2012 10:10

    Content type: Research

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  30. Nanotechnology-based bioassays that detect the presence and/or absence of a combination of cell markers are increasingly used to identify stem or progenitor cells, assess cell heterogeneity, and evaluate tumor...

    Authors: Veronica Dudu, Veronica Rotari and Maribel Vazquez

    Citation: Journal of Nanobiotechnology 2012 10:9

    Content type: Research

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  31. In situation like diagnosis of clinical and forensic samples there exists a need for highly sensitive, rapid and specific DNA detection methods. Though conventional DNA amplification using PCR can provide fast...

    Authors: Padmavathy Bakthavathsalam, Vinoth Kumar Rajendran and Jaffar Ali Baquir Mohammed

    Citation: Journal of Nanobiotechnology 2012 10:8

    Content type: Research

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  32. Gene transfer using non-viral vectors offers a non-immunogenic and safe method of gene delivery. Cellular uptake and intracellular trafficking of the nanoparticles can impact on the transfection efficiency of ...

    Authors: Jagbir Singh, Deborah Michel, Jackson M Chitanda, Ronald E Verrall and Ildiko Badea

    Citation: Journal of Nanobiotechnology 2012 10:7

    Content type: Research

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  33. The design of biomimetic materials that parallel the morphology and biology of extracellular matrixes is key to the ability to grow functional tissues in vitro and to enhance the integration of biomaterial implan...

    Authors: Jamie L Hass, Erin M Garrison, Sarah A Wicher, Ben Knapp, Nathan Bridges, DN Mcllroy and Gustavo Arrizabalaga

    Citation: Journal of Nanobiotechnology 2012 10:6

    Content type: Research

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  34. Nanoparticles (NPs) can potentially cause adverse effects on organ, tissue, cellular, subcellular and protein levels due to their unusual physicochemical properties. Advances in nanotechnology have identified ...

    Authors: Mohamed Anwar K Abdelhalim and Bashir M Jarrar

    Citation: Journal of Nanobiotechnology 2012 10:5

    Content type: Research

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  35. The inherent toxicity of unmodified Quantum Dots (QDs) is a major hindrance to their use in biological applications. To make them more potent as neuroprosthetic and neurotherapeutic agents, thioglycolic acid (...

    Authors: Babu R Prasad, Gillian Mullins, Natalia Nikolskaya, David Connolly, Terry J Smith, Valérie A Gérard, Stephen J Byrne, Gemma-Louise Davies, Yurii K Gun'ko and Yury Rochev

    Citation: Journal of Nanobiotechnology 2012 10:4

    Content type: Research

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  36. Fe3O4-gold-chitosan core-shell nanostructure can be used in biotechnological and biomedical applications such as magnetic bioseparation, water and wastewater treatment, biodetection and bioimaging, drug delivery,...

    Authors: Hossein Salehizadeh, Elham Hekmatian, Meisam Sadeghi and Kevin Kennedy

    Citation: Journal of Nanobiotechnology 2012 10:3

    Content type: Research

    Published on:

  37. Efficient delivery of anticancer chemotherapies such as paclitaxel (PTX) can improve treatment strategy in a variety of tumors such as breast and ovarian cancers. Accordingly, researches on polymeric nanomicel...

    Authors: Ahmad Yari Khosroushahi, Hossein Naderi-Manesh, Hamid Yeganeh, Jaleh Barar and Yadollah Omidi

    Citation: Journal of Nanobiotechnology 2012 10:2

    Content type: Research

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  38. The need to functionalize cell membranes in a directed way for specific applications as single cell arrays or to force close cell-to-cell contact for artificial intercellular interaction and/or induction conce...

    Authors: Markus von Nickisch-Rosenegk, Till Teschke and Frank F Bier

    Citation: Journal of Nanobiotechnology 2012 10:1

    Content type: Research

    Published on:

  39. Light-directed in situ synthesis of DNA microarrays using computer-controlled projection from a digital micromirror device--maskless array synthesis (MAS)--has proved to be successful at both commercial and labor...

    Authors: Christy Agbavwe, Changhan Kim, DongGee Hong, Kurt Heinrich, Tao Wang and Mark M Somoza

    Citation: Journal of Nanobiotechnology 2011 9:57

    Content type: Research

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  40. Elucidation of molecular mechanism of silver nanoparticles (SNPs) biosynthesis is important to control its size, shape and monodispersity. The evaluation of molecular mechanism of biosynthesis of SNPs is of pr...

    Authors: Indu Barwal, Peeyush Ranjan, Suneel Kateriya and Subhash Chandra Yadav

    Citation: Journal of Nanobiotechnology 2011 9:56

    Content type: Research

    Published on:

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