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  1. Content type: Research

    We developed a non-viral vector, a combination of HIV-1 Tat peptide modified with histidine and cysteine (mTat) and polyethylenimine, jetPEI (PEI), displaying the high efficiency of plasmid DNA transfection wi...

    Authors: Hironori Kasai, Kenji Inoue, Kentaro Imamura, Carlo Yuvienco, Jin K. Montclare and Seiichi Yamano

    Citation: Journal of Nanobiotechnology 2019 17:11

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  2. Content type: Research

    Osteoporosis is a bone-incapacitating malady and it is characterized by obvious bone mass loss and bone microarchitecture deterioration. Current treatments for osteoporosis have many limitations, including the...

    Authors: Xiaoduan Sun, Jun Wei, Jiayao Lyu, Tierong Bian, Zhongbing Liu, Juan Huang, Fengjuan Pi, Chunhong Li and Zhirong Zhong

    Citation: Journal of Nanobiotechnology 2019 17:10

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  3. Content type: Research

    Leading to more and more deaths and disabilities, stroke has become a serious threat to human health. What’s more, few effective drugs are available in clinic till now.

    Authors: Xiangrui Yang, Lanxi Xu, Juan Zhou, Yunlong Ge, Shichao Wu, Junxiong Huang, Ying Li, Maoshu Zhu, Xin Jin and Lichao Yang

    Citation: Journal of Nanobiotechnology 2019 17:8

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  4. Content type: Research

    The rationale of this study is to combine the merits of both albumin nanoparticles and quantum dots (QDs) in improved drug tumor accumulation and strong fluorescence imaging capability into one carrier. Howeve...

    Authors: Dina G. Zayed, Shaker M. Ebrahim, Maged W. Helmy, Sherine N. Khattab, Mohammed Bahey-El-Din, Jia-You Fang, Kadria A. Elkhodairy and Ahmed O. Elzoghby

    Citation: Journal of Nanobiotechnology 2019 17:7

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  5. Content type: Research

    Helicobacter pylori (H. pylori) infection remains a global public health issue, especially in Asia. Due to the emergence of antibiotic-resistant strains and the complexity of H. pylori infection, conventional vac...

    Authors: Yun Yang, Li Chen, Hong-wu Sun, Hong Guo, Zhen Song, Ying You, Liu-yang Yang, Ya-nan Tong, Ji-ning Gao, Hao Zeng, Wu-chen Yang and Quan-ming Zou

    Citation: Journal of Nanobiotechnology 2019 17:6

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  6. Content type: Retraction Note

    The Editors have retracted this article [1] because Figs. 6a and 6c have been used in three other publications to represent scanning electron micrographs of different nanoparticles [2–4]. The data reported in ...

    Authors: Abolfazl Akbarzadeh, Mohammad Samiei, Sang Woo Joo, Maryam Anzaby, Younes Hanifehpour, Hamid Tayefi Nasrabadi and Soodabeh Davaran

    Citation: Journal of Nanobiotechnology 2019 17:5

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    The original article was published in Journal of Nanobiotechnology 2012 10:46

  7. Content type: Correction

    After publication of the original article [1], an error was noted in the author affiliation. Lin Long is also affiliated to the College of Opto-electronic Engineering, Zaozhuang University, Zaozhuang, China, w...

    Authors: Lin Long, Jianbo Liu, Kaishun Lu, Tao Zhang, Yunqing Xie, Yinglu Ji and Xiaochun Wu

    Citation: Journal of Nanobiotechnology 2019 17:4

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    The original article was published in Journal of Nanobiotechnology 2018 16:46

  8. Content type: Research

    Retinal degeneration diseases affect millions of patients worldwide and lead to incurable vision loss. These diseases are caused by pathologies in the retina and underlying choroid, located in the back of the ...

    Authors: Adi Tzameret, Hadas Ketter-Katz, Victoria Edelshtain, Ifat Sher, Enav Corem-Salkmon, Itay Levy, David Last, David Guez, Yael Mardor, Shlomo Margel and Ygal Rotenstrich

    Citation: Journal of Nanobiotechnology 2019 17:3

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  9. Content type: Research

    Previous studies have demonstrated that exposure to nickel nanoparticles (Nano-Ni) causes oxidative stress and severe, persistent lung inflammation, which are strongly associated with pulmonary toxicity. Howev...

    Authors: Yiqun Mo, Mizu Jiang, Yue Zhang, Rong Wan, Jing Li, Chuan-Jian Zhong, Huangyuan Li, Shichuan Tang and Qunwei Zhang

    Citation: Journal of Nanobiotechnology 2019 17:2

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  10. Content type: Research

    Tumor-derived exosomes are gaining attention as important factors that facilitate communication between neighboring cells and manipulate cellular processes associated with cancer development or progression. Th...

    Authors: Jiyun Lim, Mihye Choi, HyungJae Lee, Young-Ho Kim, Ji-Youn Han, Eun Sook Lee and Youngnam Cho

    Citation: Journal of Nanobiotechnology 2019 17:1

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  11. Content type: Research

    Acute lung injury (ALI) is a life-threatening clinical syndrome without effective treatment. Targeting delivery of glucocorticoid to lung shows potential efficacy for ALI based on their anti-inflammatory and a...

    Authors: Shujuan Li, Li Chen, Guokang Wang, Lexing Xu, Shanshan Hou, Ziwei Chen, Xiaoling Xu, Xiaojuan Wang, Fuhe Liu and Yong-Zhong Du

    Citation: Journal of Nanobiotechnology 2018 16:105

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  12. Content type: Research

    Recently, a combination of photodynamic therapy (PDT) and photothermal therapy (PTT) to generate reactive oxygen species (ROS) and heat to kill cancer cells, respectively has attracted considerable attention b...

    Authors: Jooran Lee, Young Hwa Lee, Chan Bae Jeong, Joon Sig Choi, Ki Soo Chang and Minjoong Yoon

    Citation: Journal of Nanobiotechnology 2018 16:104

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  13. Content type: Research

    Sorafenib is an effective clinical drug in therapy of hepatocellular carcinoma, having led to improved prognosis in hepatocellular carcinoma patients. However acquired resistance is still being encountered. So...

    Authors: Hongdan Li, Cheng Yang, Yijie Shi and Liang Zhao

    Citation: Journal of Nanobiotechnology 2018 16:103

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  14. Content type: Review

    Atomic force microscopy (AFM) allows for nanometer-scale investigation of cells and molecules. Recent advances have enabled its application in cancer research and diagnosis. The physicochemical properties of l...

    Authors: Xiangying Deng, Fang Xiong, Xiayu Li, Bo Xiang, Zheng Li, Xu Wu, Can Guo, Xiaoling Li, Yong Li, Guiyuan Li, Wei Xiong and Zhaoyang Zeng

    Citation: Journal of Nanobiotechnology 2018 16:102

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  15. Content type: Research

    We introduce a self-assembling polypeptide-based nanotube system having the ability to specifically target cancer cells. The nanotubes target the cancer cell surface through integrin engagement with the help o...

    Authors: Gitanjali Asampille, Brijesh Kumar Verma, Monalisa Swain, Abhijith Shettar, Steven A. Rosenzweig, Paturu Kondaiah and Hanudatta S. Atreya

    Citation: Journal of Nanobiotechnology 2018 16:101

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  16. Content type: Research

    Particokinetic models are important to predict the effective cellular dose, which is key to understanding the interactions of particles with biological systems. For the reliable establishment of dose–response ...

    Authors: Thomas Kowoll, Susanne Fritsch-Decker, Silvia Diabaté, Gerd Ulrich Nienhaus, Dagmar Gerthsen and Carsten Weiss

    Citation: Journal of Nanobiotechnology 2018 16:100

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  17. Content type: Research

    Cancer stem cells (CSCs) are highly proliferative and tumorigenic, which contributes to chemotherapy resistance and tumor occurrence. CSCs specific therapy may achieve excellent therapeutic effects, especially...

    Authors: Yuanyuan Li, Sanjun Shi, Yue Ming, Linli Wang, Chenwen Li, Minghe Luo, Ziwei Li, Bin Li and Jianhong Chen

    Citation: Journal of Nanobiotechnology 2018 16:99

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  18. Content type: Research

    Sustained drug delivery is a large unmet clinical need in glaucoma. Here, we incorporated a Myocardin-Related Transcription Factor/Serum Response Factor inhibitor, CCG-222740, into slow release large unilamell...

    Authors: Aristides D. Tagalakis, Shivam Madaan, Scott D. Larsen, Richard R. Neubig, Peng T. Khaw, Ian Rodrigues, Saurabh Goyal, Kin Sheng Lim and Cynthia Yu-Wai-Man

    Citation: Journal of Nanobiotechnology 2018 16:97

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  19. Content type: Research

    In orthopedic surgery, implant-associated infections are still a major problem. For the improvement of the selective therapy in the infection area, magnetic nanoparticles as drug carriers are promising when us...

    Authors: Hilke Catherina Janßen, Dawid Peter Warwas, David Dahlhaus, Jessica Meißner, Piriya Taptimthong, Manfred Kietzmann, Peter Behrens, Janin Reifenrath and Nina Angrisani

    Citation: Journal of Nanobiotechnology 2018 16:96

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  20. Content type: Review

    The need and desire to understand the environment, especially the quality of one’s local water and air, has continued to expand with the emergence of the digital age. The bottleneck in understanding the enviro...

    Authors: Marjorie R. Willner and Peter J. Vikesland

    Citation: Journal of Nanobiotechnology 2018 16:95

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  21. Content type: Research

    Modern agricultural practises rely on surfactant-based spray applications to eliminate weeds in crops. The wide spread and indiscriminate use of surfactants may result in a number of deleterious effects that a...

    Authors: Pavani P. Nadiminti, Qingtao Liu, Lavanya K. Vanjari, Yao D. Dong, Ben J. Boyd and David M. Cahill

    Citation: Journal of Nanobiotechnology 2018 16:94

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  22. Content type: Research

    Given the great benefits of artificial enzymes, a simple approach is proposed via assembling of Ni2+ with hemin for synthesis of Ni-hemin metal–organic-frameworks (Ni-hemin MOFs) mimic enzyme. The formation of th...

    Authors: Negar Alizadeh, Abdollah Salimi, Rahman Hallaj, Fardin Fathi and Farzad Soleimani

    Citation: Journal of Nanobiotechnology 2018 16:93

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  23. Content type: Research

    Atherosclerosis, a major source of cardiovascular disease, is asymptomatic for decades until the activation of thrombosis and the rupture of enlarged plaques, resulting in acute coronary syndromes and sudden c...

    Authors: Christopher Poon, Juan Gallo, Johan Joo, Timothy Chang, Manuel Bañobre-López and Eun Ji Chung

    Citation: Journal of Nanobiotechnology 2018 16:92

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  24. Content type: Research

    Microdialysis is promising technique for dynamic microbiochemical sampling from tissues. However, the application of typical aqueous perfusates to liposoluble substances is limited. In this study, a novel micr...

    Authors: Yong-Tai Zhang, Zhi Wang, Li-Na Shen, Yan-Yan Li, Ze-Hui He, Qing Xia and Nian-Ping Feng

    Citation: Journal of Nanobiotechnology 2018 16:91

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  25. Content type: Research

    In the last decade, the biosynthesis of metal nanoparticles using organisms have received more and more considerations. However, the complex composition of organisms adds up to a great barrier for the characte...

    Authors: Shichao Wu, Xiangrui Yang, Fanghong Luo, Ting Wu, Peilan Xu, Mingyuan Zou and Jianghua Yan

    Citation: Journal of Nanobiotechnology 2018 16:90

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  26. Content type: Research

    Developing an ideal wound dressing that meets the multiple demands of good biocompatibility, an appropriate porous structure, superior mechanical property and excellent antibacterial activity against drug-resi...

    Authors: Menglong Liu, Tengfei Liu, Xiwei Chen, Jiacai Yang, Jun Deng, Weifeng He, Xiaorong Zhang, Qiang Lei, Xiaohong Hu, Gaoxing Luo and Jun Wu

    Citation: Journal of Nanobiotechnology 2018 16:89

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  27. Content type: Research

    We have previously shown that intraperitoneal injection of gold nanoparticles (AuNPs, 20–30 nm) into mice, decreases high-fat diet (HFD) induced weight gain and glucose intolerance, via suppression of inflamma...

    Authors: Hui Chen, Jane P. M. Ng, David P. Bishop, Bruce K. Milthorpe and Stella M. Valenzuela

    Citation: Journal of Nanobiotechnology 2018 16:88

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  28. Content type: Review

    Oxidative stress (OS) and nitrative stress (NS) accompany many diseases, including Alzheimer’s disease (AD) and Parkinson’s disease (PD). Antioxidants have been proposed to counteract OS/NS in these diseases. ...

    Authors: Izabela Sadowska-Bartosz and Grzegorz Bartosz

    Citation: Journal of Nanobiotechnology 2018 16:87

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  29. Content type: Research

    Gold nanoparticles (AuNPs) are attracting interest as potential therapeutic agents to treat inflammatory diseases, but their anti-inflammatory mechanism of action is not clear yet. In addition, the effect of o...

    Authors: Suqin Zhu, Xiumei Jiang, Mary D. Boudreau, Guangxin Feng, Yu Miao, Shiyuan Dong, Haohao Wu, Mingyong Zeng and Jun-Jie Yin

    Citation: Journal of Nanobiotechnology 2018 16:86

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  30. Content type: Research

    The biomedical use of nanosized materials is rapidly gaining interest, which drives the quest to elucidate the behavior of nanoparticles (NPs) in a biological environment. Apart from causing direct cell death,...

    Authors: Bella B. Manshian, Suman Pokhrel, Lutz Mädler and Stefaan J. Soenen

    Citation: Journal of Nanobiotechnology 2018 16:85

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  31. Content type: Review

    In materials science, “green” synthesis has gained extensive attention as a reliable, sustainable, and eco-friendly protocol for synthesizing a wide range of materials/nanomaterials including metal/metal oxid...

    Authors: Jagpreet Singh, Tanushree Dutta, Ki-Hyun Kim, Mohit Rawat, Pallabi Samddar and Pawan Kumar

    Citation: Journal of Nanobiotechnology 2018 16:84

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  32. Content type: Research

    In order to explore the possibility of treating breast cancer by local photo-therapy, a photothermal agents loaded in situ hydrogel was established. In detail, The Cu2MnS2 nanoplates were prepared by one-pot synt...

    Authors: Ji-jun Fu, Ming-yue Chen, Jie-xia Li, Jun-hua Zhou, Sheng-nan Xie, Ping Yuan, Bo Tang and Cheng-cheng Liu

    Citation: Journal of Nanobiotechnology 2018 16:83

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  33. Content type: Research

    The continuously growing human exposure to combustion-derived particles (CDPs) drives in depth investigation of the involved complex toxicological mechanisms of those particles. The current study evaluated the...

    Authors: Hannelore Bové, Jens Devoght, Leentje Rasking, Martijn Peters, Eli Slenders, Maarten Roeffaers, Alvaro Jorge-Peñas, Hans Van Oosterwyck and Marcel Ameloot

    Citation: Journal of Nanobiotechnology 2018 16:82

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  34. Content type: Review

    Extracellular vesicles (EVs) are the substances that are released by most types of cells and have an important role in cell to cell communication. Among the most highly researched EVs are exosome. Recent studi...

    Authors: Edwin J. Bunggulawa, Wei Wang, Tieying Yin, Nan Wang, Colm Durkan, Yazhou Wang and Guixue Wang

    Citation: Journal of Nanobiotechnology 2018 16:81

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  35. Content type: Research

    Engineered inorganic nanoparticles (NPs) are essential components in the development of nanotechnologies. For applications in nanomedicine, particles need to be functionalized to ensure a good dispersibility i...

    Authors: Muhammad Raisul Abedin, Siddesh Umapathi, Harika Mahendrakar, Tunyaboon Laemthong, Holly Coleman, Denise Muchangi, Santimukul Santra, Manashi Nath and Sutapa Barua

    Citation: Journal of Nanobiotechnology 2018 16:80

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  36. Content type: Research

    Gold nanoparticles (AuNPs) are promising candidates to design the next generation NP-based drug formulations specifically treating maternal, fetal or placental complications with reduced side effects. Profound...

    Authors: Leonie Aengenheister, Dörthe Dietrich, Amin Sadeghpour, Pius Manser, Liliane Diener, Adrian Wichser, Uwe Karst, Peter Wick and Tina Buerki-Thurnherr

    Citation: Journal of Nanobiotechnology 2018 16:79

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  37. Content type: Research

    Differentiation of telomere length is of vital importance because telomere length is closely related with several deadly diseases such as cancer. Additionally, G-quadruplex and i-motif formation in telomeric D...

    Authors: Shuai Wang, Fei Qu, Wenli Han and Jinmao You

    Citation: Journal of Nanobiotechnology 2018 16:78

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  38. Content type: Research

    Effectiveness of chemotherapy for treating glioblastoma (GBM) brain tumors is hampered by the blood–brain barrier which limits the entry into the brain of most drugs from the blood. To bypass this barrier, con...

    Authors: Minghan Shi, Malathi Anantha, Mohamed Wehbe, Marcel B. Bally, David Fortin, Laurent-Olivier Roy, Gabriel Charest, Maxime Richer, Benoit Paquette and Léon Sanche

    Citation: Journal of Nanobiotechnology 2018 16:77

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  39. Content type: Research

    Recently, we found that berberine (BBR) exerts anti-acute myeloid leukemia activity, particularly toward high-risk and relapsed/refractory acute myeloid leukemia MV4-11 cells in vitro. However, the poor water ...

    Authors: Jieping Li, Li Yang, Rui Shen, Li Gong, Zhiqiang Tian, Huarong Qiu, Zhe Shi, Lichen Gao, Hongwu Sun and Guangsen Zhang

    Citation: Journal of Nanobiotechnology 2018 16:76

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  40. Content type: Review

    Graphene’s unique physical structure, as well as its chemical and electrical properties, make it ideal for use in sensor technologies. In the past years, novel sensing platforms have been proposed with pristin...

    Authors: Janire Peña-Bahamonde, Hang N. Nguyen, Sofia K. Fanourakis and Debora F. Rodrigues

    Citation: Journal of Nanobiotechnology 2018 16:75

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  41. Content type: Review

    With the improvement of nanotechnology and nanomaterials, redox-responsive delivery systems have been studied extensively in some critical areas, especially in the field of biomedicine. The system constructed...

    Authors: Xiaoshuang Guo, Yuan Cheng, Xiaotian Zhao, Yanli Luo, Jianjun Chen and Wei-En Yuan

    Citation: Journal of Nanobiotechnology 2018 16:74

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  42. Content type: Research

    Galectin-3 (Gal-3) is a promising target in cancer therapy with a high therapeutic potential due to its abundant localization within the tumor tissue and its involvement in tumor development and proliferation....

    Authors: P. Bojarová, M. R. Tavares, D. Laaf, L. Bumba, L. Petrásková, R. Konefał, M. Bláhová, H. Pelantová, L. Elling, T. Etrych, P. Chytil and V. Křen

    Citation: Journal of Nanobiotechnology 2018 16:73

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  43. Content type: Research

    Messenger RNA (mRNA) has gained remarkable attention as an alternative to DNA-based therapies in biomedical research. A variety of biodegradable nanoparticles (NPs) has been developed including lipid-based and...

    Authors: Hanzey Yasar, Alexander Biehl, Chiara De Rossi, Marcus Koch, Xabi Murgia, Brigitta Loretz and Claus-Michael Lehr

    Citation: Journal of Nanobiotechnology 2018 16:72

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  44. Content type: Review

    Nanomedicine and nano delivery systems are a relatively new but rapidly developing science where materials in the nanoscale range are employed to serve as means of diagnostic tools or to deliver therapeutic ag...

    Authors: Jayanta Kumar Patra, Gitishree Das, Leonardo Fernandes Fraceto, Estefania Vangelie Ramos Campos, Maria del Pilar Rodriguez-Torres, Laura Susana Acosta-Torres, Luis Armando Diaz-Torres, Renato Grillo, Mallappa Kumara Swamy, Shivesh Sharma, Solomon Habtemariam and Han-Seung Shin

    Citation: Journal of Nanobiotechnology 2018 16:71

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  45. Content type: Research

    Upon ingestion, nanoparticles can interact with the intestinal epithelial barrier potentially resulting in systemic uptake of nanoparticles. Nanoparticle properties have been described to influence the protein...

    Authors: Ashraf Abdelkhaliq, Meike van der Zande, Ans Punt, Richard Helsdingen, Sjef Boeren, Jacques J. M. Vervoort, Ivonne M. C. M. Rietjens and Hans Bouwmeester

    Citation: Journal of Nanobiotechnology 2018 16:70

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  46. Content type: Research

    Porphyromonas gingivalis adherence to oral streptococci is a key point in the pathogenesis of periodontal diseases (Honda in Cell Host Microbe 10:423–425, 2011). Previous work in our groups has shown that a regio...

    Authors: Mohamed Y. Mahmoud, Donald R. Demuth and Jill M. Steinbach-Rankins

    Citation: Journal of Nanobiotechnology 2018 16:69

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  47. Content type: Research

    In recent years, nanoparticles (NPs) including nanostructured lipid carries (NLC) and solid lipid nanoparticles (SLN) captured an increasing amount of attention in the field of transdermal drug delivery system...

    Authors: Yongwei Gu, Meng Yang, Xiaomeng Tang, Ting Wang, Dishun Yang, Guangxi Zhai and Jiyong Liu

    Citation: Journal of Nanobiotechnology 2018 16:68

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  48. Content type: Short Communication

    Intracellular protein and proteomic studies using mass spectrometry, imaging microscopy, flow cytometry, or western blotting techniques require genetic manipulation, cell permeabilization, and/or cell lysis. W...

    Authors: Elaheh Shekaramiz, Rupak Doshi and H. Kumar Wickramasinghe

    Citation: Journal of Nanobiotechnology 2018 16:67

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  49. Content type: Research

    Due to the high transfer ability of cancer cell, cancer has been regarded as a world-wide high mortality disease. Quantitative analysis of circulating tumor cells (CTCs) can provide some valuable clinical info...

    Authors: Xuan Wu, Tingyu Xiao, Zhang Luo, Rongxiang He, Yiping Cao, Zhenzhong Guo, Weiying Zhang and Yong Chen

    Citation: Journal of Nanobiotechnology 2018 16:65

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