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  1. Content type: Research

    Flexuous rod-shaped nanoparticles made of the coat protein (CP) of papaya mosaic virus (PapMV) have been shown to trigger innate immunity through engagement of toll-like receptor 7 (TLR7). PapMV nanoparticles ...

    Authors: Ariane Thérien, Mikaël Bédard, Damien Carignan, Gervais Rioux, Louis Gauthier-Landry, Marie-Ève Laliberté-Gagné, Marilène Bolduc, Pierre Savard and Denis Leclerc

    Citation: Journal of Nanobiotechnology 2017 15:54

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  2. Content type: Research

    In addition to conventional chemotherapeutics, nucleic acid-based therapeutics like antisense oligodeoxynucleotides (AS-ODN) represent a novel approach for the treatment of bladder cancer (BCa). An efficient d...

    Authors: Anika Kaufmann, Silke Hampel, Christiane Rieger, David Kunhardt, Darja Schendel, Susanne Füssel, Bernd Schwenzer and Kati Erdmann

    Citation: Journal of Nanobiotechnology 2017 15:53

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  3. Content type: Letter to the Editor

    Moth-eye nanostructures, discovered to coat corneae of certain nocturnal insects, have inspired numerous technological applications to reduce light reflectance from solar cells, light-emitting diodes, and opti...

    Authors: Mikhail Kryuchkov, Jannis Lehmann, Jakob Schaab, Manfred Fiebig and Vladimir L. Katanaev

    Citation: Journal of Nanobiotechnology 2017 15:52

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  4. Content type: Research

    Nutrient-containing nanomaterials have been developed as fertilizers to foster plant growth and agricultural yield through root applications. However, if applied through leaves, how these nanomaterials, e.g. γ-Fe

    Authors: Jing Hu, Huiyuan Guo, Junli Li, Yunqiang Wang, Lian Xiao and Baoshan Xing

    Citation: Journal of Nanobiotechnology 2017 15:51

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  5. Content type: Research

    Increasing production of nanomaterials requires fast and proper assessment of its potential toxicity. Therefore, there is a need to develop new assays that can be performed in vitro, be cost effective, and all...

    Authors: Yan Xu, M. Hadjiargyrou, Miriam Rafailovich and Tatsiana Mironava

    Citation: Journal of Nanobiotechnology 2017 15:50

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  6. Content type: Research

    Nanomedicine offers a promising tool for therapies of brain diseases, but potential effects on neuronal health and neuronal differentiation need to be investigated to assess potential risks. The aim of this st...

    Authors: Angélique D. Ducray, Andrea Felser, Jana Zielinski, Aniela Bittner, Julia V. Bürgi, Jean-Marc Nuoffer, Martin Frenz and Meike Mevissen

    Citation: Journal of Nanobiotechnology 2017 15:49

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  7. Content type: Research

    Significant progress of nanotechnology, including in particular biomedical and pharmaceutical applications, has resulted in a high number of studies describing the biological effects of nanomaterials. Moreover...

    Authors: Blanka Halamoda-Kenzaoui, Mara Ceridono, Patricia Urbán, Alessia Bogni, Jessica Ponti, Sabrina Gioria and Agnieszka Kinsner-Ovaskainen

    Citation: Journal of Nanobiotechnology 2017 15:48

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  8. Content type: Research

    Understanding the interaction of graphene-related materials (GRM) with human cells is a key to the assessment of their potential risks for human health. There is a knowledge gap regarding the potential uptake ...

    Authors: Melanie Kucki, Liliane Diener, Nils Bohmer, Cordula Hirsch, Harald F. Krug, Vincenzo Palermo and Peter Wick

    Citation: Journal of Nanobiotechnology 2017 15:46

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  9. Content type: Research

    Nanoparticle interactions with cellular membranes and the kinetics of their transport and localization are important determinants of their functionality and their biological consequences. Understanding these p...

    Authors: Bella B. Manshian, Thomas F. Martens, Karsten Kantner, Kevin Braeckmans, Stefaan C. De Smedt, Jo Demeester, Gareth J. S. Jenkins, Wolfgang J. Parak, Beatriz Pelaz, Shareen H. Doak, Uwe Himmelreich and Stefaan J. Soenen

    Citation: Journal of Nanobiotechnology 2017 15:45

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  10. Content type: Research

    Antimicrobial peptides (AMPs) have the potential to serve as an alternative to antibiotic. AMPs usually exert bactericidal activity via direct killing of microbial pathogens. Reports have proposed that by harn...

    Authors: Biswaranjan Pradhan, Dipanjan Guha, Krushna Chandra Murmu, Abhinav Sur, Pratikshya Ray, Debashmita Das and Palok Aich

    Citation: Journal of Nanobiotechnology 2017 15:44

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  11. Content type: Research

    Selenium is well documented to inhibit cancer at higher doses; however, the mechanism behind this inhibition varies widely depending on the cell type and selenium species. Previously, we have demonstrated that Ba...

    Authors: Praveen Sonkusre and Swaranjit Singh Cameotra

    Citation: Journal of Nanobiotechnology 2017 15:43

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  12. Content type: Research

    Iron deficiency in children can have significant neurological consequences, and iron supplementation is an effective treatment of choice. However, traditional routes of iron supplementation do not allow effici...

    Authors: Xueling Guo, Hong Zheng, Yuetong Guo, Yan Wang, Gregory J. Anderson, Yunzhe Ci, Peng Yu, Lina Geng and Yan-Zhong Chang

    Citation: Journal of Nanobiotechnology 2017 15:42

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  13. Content type: Research

    Breast cancer is the most frequently diagnosed cancer and the leading cause of cancer death among females worldwide. Among various types of breast cancer, the human epidermal growth factor receptor 2 (HER2)-ov...

    Authors: Yu-Hsiang Lee and Yun-Ting Ma

    Citation: Journal of Nanobiotechnology 2017 15:41

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  14. Content type: Research

    The object of this study was to develop a thermally and reactive oxygen species-responsive nanocarrier system for cancer therapy.

    Authors: Meiqiong Tang, Ping Hu, Qiang Zheng, Nicola Tirelli, Xiaohong Yang, Zhanlong Wang, Yanfang Wang, Qing Tang and Yun He

    Citation: Journal of Nanobiotechnology 2017 15:39

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  15. Content type: Short Communication

    Quantum dot (QD)-based single virus tracking has become a powerful tool for dissecting virus infection mechanism. However, only virus behaviors at the early stage of retrograde trafficking have been dynamicall...

    Authors: Li Wen, Zhen-Hua Zheng, An-An Liu, Cheng Lv, Li-Juan Zhang, Jian Ao, Zhi-Ling Zhang, Han-Zhong Wang, Yi Lin and Dai-Wen Pang

    Citation: Journal of Nanobiotechnology 2017 15:37

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  16. Content type: Research

    Gold–polyamidoamine (AuPAMAM) has previously been shown to successfully transfect cells with high efficiency. However, we have observed that certain cell types are more amenable to Au–PAMAM transfection than o...

    Authors: Elizabeth Figueroa, Pallavi Bugga, Vishwaratn Asthana, Allen L. Chen, J. Stephen Yan, Emily Reiser Evans and Rebekah A. Drezek

    Citation: Journal of Nanobiotechnology 2017 15:36

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  17. Content type: Research

    The conventional and widely used enzyme-linked immunosorbent assays (ELISA), due to specificity and high-sensitivity, were suitable in vitro diagnosis. But enzymes are vulnerable to the external conditions, an...

    Authors: Yanbing Lv, Ruili Wu, Kunrui Feng, Jinjie Li, Qing Mao, Hang Yuan, Huaibin Shen, Xiangdong Chai and Lin Song Li

    Citation: Journal of Nanobiotechnology 2017 15:35

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  18. Content type: Research

    Small interfering RNAs (siRNAs) are powerful tools to control gene expression. However, due to their poor cellular permeability and stability, their therapeutic development requires a specific delivery system....

    Authors: Anaïs Vaissière, Gudrun Aldrian, Karidia Konate, Mattias F. Lindberg, Carole Jourdan, Anthony Telmar, Quentin Seisel, Frédéric Fernandez, Véronique Viguier, Coralie Genevois, Franck Couillaud, Prisca Boisguerin and Sébastien Deshayes

    Citation: Journal of Nanobiotechnology 2017 15:34

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  19. Content type: Review

    Nanomaterials in agriculture are becoming popular due to the impressive advantages of these particles. However, their bioavailability and toxicity are key features for their massive employment. Herein, we comp...

    Authors: Branislav Ruttkay-Nedecky, Olga Krystofova, Lukas Nejdl and Vojtech Adam

    Citation: Journal of Nanobiotechnology 2017 15:33

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  20. Content type: Research

    Bacteriophage survives in at least two extremes of ionic environments: bacterial host (high ionic-cytosol) and that of soil (low ionic-environmental water). The impact of ionic composition in the micro- and macro...

    Authors: Bożena Szermer-Olearnik, Marek Drab, Mateusz Mąkosa, Maria Zembala, Jakub Barbasz, Krystyna Dąbrowska and Janusz Boratyński

    Citation: Journal of Nanobiotechnology 2017 15:32

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  21. Content type: Research

    The widespread application of silver nanoparticles (AgNPs) and silver-containing products has raised public safety concerns about their adverse effects on human health and the environment. To date, in vitro to...

    Authors: Xiugong Gao, Vanessa D. Topping, Zachary Keltner, Robert L. Sprando and Jeffrey J. Yourick

    Citation: Journal of Nanobiotechnology 2017 15:31

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  22. Content type: Review

    Neurological diseases of diverse aetiologies have significant effects on the quality of life of patients. The limited self-repairing capacity of the brain is considered to be the origin of the irreversible and...

    Authors: Andrés Da Silva-Candal, Bárbara Argibay, Ramón Iglesias-Rey, Zulema Vargas, Alba Vieites-Prado, Esteban López-Arias, Emilio Rodríguez-Castro, Iria López-Dequidt, Manuel Rodríguez-Yáñez, Yolanda Piñeiro, Tomás Sobrino, Francisco Campos, José Rivas and José Castillo

    Citation: Journal of Nanobiotechnology 2017 15:30

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  23. Content type: Research

    Carbapenem-resistance is an extremely growing medical threat in antibacterial therapy as the incurable resistant strains easily develop a multi-resistance action to other potent antimicrobial agents. Nonethele...

    Authors: Mona I. Shaaban, Mohamed A. Shaker and Fatma M. Mady

    Citation: Journal of Nanobiotechnology 2017 15:29

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  24. Content type: Research

    Autophagy reportedly plays vital and complex roles in many diseases. During times of starvation or energy deficiency, autophagy will occur at higher levels to provide cells with the nutrients or energy necessa...

    Authors: Yan Zheng, Chang Su, Liang Zhao and Yijie Shi

    Citation: Journal of Nanobiotechnology 2017 15:28

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  25. Content type: Research

    Tracking targets of natural products is one of the most challenging issues in fields ranging from pharmacognosy to biomedicine. It is widely recognized that the biocompatible nanoparticle (NP) could function a...

    Authors: Qingxin Cui, Yuanyuan Hou, Yanan Wang, Xu Li, Yang Liu, Xiaoyao Ma, Zengyong Wang, Weiya Wang, Jin Tao, Qian Wang, Min Jiang, Dongyan Chen, Xizeng Feng and Gang Bai

    Citation: Journal of Nanobiotechnology 2017 15:27

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  26. Content type: Research

    Dengue is the most prevalent arthropod-borne viral disease in the world. In this article we present results on the development, characterization and immunogenic evaluation of an alternative vaccine candidate a...

    Authors: Alice F. Versiani, Ruiz G. Astigarraga, Eliseu S. O. Rocha, Ana Paula M. Barboza, Erna G. Kroon, Milene A. Rachid, Daniele G. Souza, Luiz O. Ladeira, Edel F. Barbosa-Stancioli, Ado Jorio and Flávio G. Da Fonseca

    Citation: Journal of Nanobiotechnology 2017 15:26

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  27. Content type: Review

    Pathogenic bacteria contribute to various globally important diseases, killing millions of people each year. Various fields of medicine currently benefit from or may potentially benefit from the use of nanotec...

    Authors: Teodora Mocan, Cristian T. Matea, Teodora Pop, Ofelia Mosteanu, Anca Dana Buzoianu, Cosmin Puia, Cornel Iancu and Lucian Mocan

    Citation: Journal of Nanobiotechnology 2017 15:25

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  28. Content type: Research

    Mesenchymal stromal cells (MSCs) have an inherent migratory capacity towards tumor tissue in vivo. With the future objective to quantify the tumor homing efficacy of MSCs, as first step in this direction we in...

    Authors: Philipp Nold, Raimo Hartmann, Neus Feliu, Karsten Kantner, Mahmoud Gamal, Beatriz Pelaz, Jonas Hühn, Xing Sun, Philipp Jungebluth, Pablo del Pino, Holger Hackstein, Paolo Macchiarini, Wolfgang J. Parak and Cornelia Brendel

    Citation: Journal of Nanobiotechnology 2017 15:24

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  29. Content type: Methodology

    The adhesion of cells to an oscillating cantilever sensitively influences the oscillation amplitude at a given frequency. Even early stages of cytotoxicity cause a change in the viscosity of the cell membrane ...

    Authors: Fang Yang, René Riedel, Pablo del Pino, Beatriz Pelaz, Alaa Hassan Said, Mahmoud Soliman, Shashank R. Pinnapireddy, Neus Feliu, Wolfgang J. Parak, Udo Bakowsky and Norbert Hampp

    Citation: Journal of Nanobiotechnology 2017 15:23

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  30. Content type: Research

    We introduce and demonstrate that the AC biosusceptometry (ACB) technique enables real-time monitoring of magnetic nanoparticles (MNPs) in the bloodstream. We present an ACB system as a simple, portable, versa...

    Authors: André G. Próspero, Caio C. Quini, Andris F. Bakuzis, Patrícia Fidelis-de-Oliveira, Gustavo M. Moretto, Fábio P. F. Mello, Marcos F. F. Calabresi, Ronaldo V. R. Matos, Ednaldo A. Zandoná, Nícholas Zufelato, Ricardo B. Oliveira and José R. A. Miranda

    Citation: Journal of Nanobiotechnology 2017 15:22

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  31. Content type: Research

    Quantification of nanoparticle (NP) uptake in cells or tissues is very important for safety assessment. Often, electron microscopy based approaches are used for this purpose, which allow imaging at very high r...

    Authors: Erik Guehrs, Michael Schneider, Christian M. Günther, Piet Hessing, Karen Heitz, Doreen Wittke, Ana López-Serrano Oliver, Norbert Jakubowski, Johanna Plendl, Stefan Eisebitt and Andrea Haase

    Citation: Journal of Nanobiotechnology 2017 15:21

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  32. Content type: Research

    Selenium (Se) is an essential micronutrient trace element and an established nutritional antioxidant. Low Se status exacerbates inflammatory bowel diseases progression, which involves hyper inflammation in the...

    Authors: Chenghui Zhu, Shuimei Zhang, Chengwei Song, Yibo Zhang, Qinjie Ling, Peter R. Hoffmann, Jun Li, Tianfeng Chen, Wenjie Zheng and Zhi Huang

    Citation: Journal of Nanobiotechnology 2017 15:20

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  33. Content type: Review

    Engineered nanomaterials (ENMs) are key drivers for the development of highly sophisticated new technologies. As all new attainments, the rapidly increasing used of ENMs raise concerns about their safety for t...

    Authors: Christian Santschi, Nadia Von Moos, Volodymyr B. Koman, Vera I. Slaveykova, Paul Bowen and Olivier J. F. Martin

    Citation: Journal of Nanobiotechnology 2017 15:19

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  34. Content type: Research

    Diabetic retinopathy is the most common complication in diabetic patients relates to high expression of VEGF and microaneurysms. Scutellarin (Scu) turned out to be effective against diabetes related vascular e...

    Authors: Jingnan Wang, Jiayun Tan, Jiahao Luo, Peilin Huang, Wuyi Zhou, Luming Chen, Lingli Long, Li-ming Zhang, Banghao Zhu, Liqun Yang and David Y. B. Deng

    Citation: Journal of Nanobiotechnology 2017 15:18

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  35. Content type: Research

    Silver nanoparticles (AgNP) are widely applied and can, upon use, be released into the aquatic environment. This raises concerns about potential impacts of AgNP on aquatic organisms. We here present a side by ...

    Authors: Yang Yue, Xiaomei Li, Laura Sigg, Marc J-F Suter, Smitha Pillai, Renata Behra and Kristin Schirmer

    Citation: Journal of Nanobiotechnology 2017 15:16

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  36. Content type: Review

    Composite materials with fibrous reinforcement often provide superior mechanical, thermal, electrical and optical properties than the matrix. Asbestos, carbon fibers and carbon nanotubes (CNTs) have been widel...

    Authors: Jing Wang, Lukas Schlagenhauf and Ari Setyan

    Citation: Journal of Nanobiotechnology 2017 15:15

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  37. Content type: Research

    This work aimed to provide useful information on the incidence of the choice of formulation in semi-solid preparations of iron-oxide nanoparticles (IONs). The appropriate analytical methods to assess the IONs ...

    Authors: Umberto M. Musazzi, Benedetta Santini, Francesca Selmin, Valentina Marini, Fabio Corsi, Raffaele Allevi, Anna M. Ferretti, Davide Prosperi, Francesco Cilurzo, Miriam Colombo and Paola Minghetti

    Citation: Journal of Nanobiotechnology 2017 15:14

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  38. Content type: Research

    In order to increase the bioavailability of hydrophilic unstable drugs like anthocyanins, we employed a polymer-based nanoparticles approach due to its unique properties such as high stability, improved bioava...

    Authors: Faiz Ul Amin, Shahid Ali Shah, Haroon Badshah, Mehtab Khan and Myeong Ok Kim

    Citation: Journal of Nanobiotechnology 2017 15:12

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  39. Content type: Research

    Poly-lactic acid nanoparticles (PLA-NP) are a type of polymeric NP, frequently used as nanomedicines, which have advantages over metallic NP such as the ability to maintain therapeutic drug levels for sustaine...

    Authors: Camila Macedo da Luz, Matthew Samuel Powys Boyles, Priscila Falagan-Lotsch, Mariana Rodrigues Pereira, Henrique Rudolf Tutumi, Eidy de Oliveira Santos, Nathalia Balthazar Martins, Martin Himly, Aniela Sommer, Ilse Foissner, Albert Duschl, José Mauro Granjeiro and Paulo Emílio Corrêa Leite

    Citation: Journal of Nanobiotechnology 2017 15:11

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  40. Content type: Research

    Neovascularization over dental implants is an imperative requisite to achieve successful osseointegration onto implanted materials. The aim of this study was to investigate the effects on in vitro angiogenesis...

    Authors: Ernesto Beltrán-Partida, Benjamín Valdéz-Salas, Aldo Moreno-Ulloa, Alan Escamilla, Mario A. Curiel, Raúl Rosales-Ibáñez, Francisco Villarreal, David M. Bastidas and José M. Bastidas

    Citation: Journal of Nanobiotechnology 2017 15:10

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  41. Content type: Research

    Currently, graphene oxide has attracted growing attention as a drug delivery system due to its unique characteristics. Furthermore, utilization of microRNAs as biomarkers and therapeutic strategies would be pa...

    Authors: Xin Zeng, Yi Yuan, Ting Wang, Han Wang, Xianyun Hu, Ziyi Fu, Gen Zhang, Bin Liu and Guangming Lu

    Citation: Journal of Nanobiotechnology 2017 15:9

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  42. Content type: Research

    Bioactive soluble carbon nanostructures, such as the C60 fullerene can bond with up to six electrons, thus serving by a powerful scavenger of reactive oxygen species similarly to many natural antioxidants, widely...

    Authors: Yurij I. Prylutskyy, Inna V. Vereshchaka, Andriy V. Maznychenko, Nataliya V. Bulgakova, Olga O. Gonchar, Olena A. Kyzyma, Uwe Ritter, Peter Scharff, Tomasz Tomiak, Dmytro M. Nozdrenko, Iryna V. Mishchenko and Alexander I. Kostyukov

    Citation: Journal of Nanobiotechnology 2017 15:8

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  43. Content type: Research

    A targeted drug nanoparticle (NP) delivery system has shown potential as a possible cancer treatment. Given its merits, such as its selective distribution at tumor sites and its controllable drug release, drug...

    Authors: Tao Wang, Jiahui Hou, Chang Su, Liang Zhao and Yijie Shi

    Citation: Journal of Nanobiotechnology 2017 15:7

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  44. Content type: Review

    Engineered nanoparticles (NPs) offer site-specific delivery, deposition and cellular uptake due to their unique physicochemical properties and were shown to modulate immune responses. The respiratory tract wit...

    Authors: Fabian Blank, Kleanthis Fytianos, Emilie Seydoux, Laura Rodriguez-Lorenzo, Alke Petri-Fink, Christophe von Garnier and Barbara Rothen-Rutishauser

    Citation: Journal of Nanobiotechnology 2017 15:6

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  45. Content type: Research

    Nanosilver shows great promise for use in industrial, consumer or medical products because of its antimicrobial properties. However, the underlying mechanisms of the effects of silver nanoparticles on human ce...

    Authors: Jean-Pierre Kaiser, Matthias Roesslein, Liliane Diener, Adrian Wichser, Bernd Nowack and Peter Wick

    Citation: Journal of Nanobiotechnology 2017 15:5

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