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  1. Content type: Research

    Elastin-like polypeptides (ELPs) are a fascinating biomaterial that has undergone copious development for a variety of therapeutic applications including as a nanoscale drug delivery vehicle. A comprehensive u...

    Authors: Markian S. Bahniuk, Abdullah K. Alshememry, Scott V. Elgersma and Larry D. Unsworth

    Citation: Journal of Nanobiotechnology 2018 16:15

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  2. Content type: Research

    Oxidative stress acts as a trigger in the course of neurodegenerative diseases and neural injuries. An antioxidant-based therapy can be effective to ameliorate the deleterious effects of oxidative stress. Resv...

    Authors: Yang Shen, Bin Cao, Noah R. Snyder, Kevin M. Woeppel, James R. Eles and Xinyan Tracy Cui

    Citation: Journal of Nanobiotechnology 2018 16:13

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  3. Content type: Research

    The process of optimization and fabrication of nanoparticle synthesis for preclinical studies can be challenging and time consuming. Traditional small scale laboratory synthesis techniques suffer from batch to...

    Authors: Andrew Gdowski, Kaitlyn Johnson, Sunil Shah, Ignacy Gryczynski, Jamboor Vishwanatha and Amalendu Ranjan

    Citation: Journal of Nanobiotechnology 2018 16:12

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  4. Content type: Research

    Obesity is a high risk for multiple metabolic disorders due to excessive influx of energy, glucose and lipid, often from a western based diet. Low-grade inflammation plays a key role in the progression of such...

    Authors: Hui Chen, Jane P. M. Ng, Yi Tan, Kristine McGrath, David P. Bishop, Brian Oliver, Yik Lung Chan, Michael B. Cortie, Bruce K. Milthorpe and Stella M. Valenzuela

    Citation: Journal of Nanobiotechnology 2018 16:11

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  5. Content type: Research

    Ag+ and Zn2+ have already been used in combinations to obtain both enhanced antibacterial effect and low cytotoxicity. Despite this, it is still unclear how the Zn2+ co-works with Ag+ in the synergistic antibacte...

    Authors: Wei Fan, Qing Sun, Yanyun Li, Franklin R. Tay and Bing Fan

    Citation: Journal of Nanobiotechnology 2018 16:10

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  6. Content type: Research

    In the photodynamic therapy (PDT), the photosensitizer absorbs light and transfers the energy of the excited state to the oxygen in the cell environment producing reactive oxygen species (ROS), that in its tur...

    Authors: Mayara Simonelly Costa dos Santos, Ana Luisa Gouvêa, Ludmilla David de Moura, Leonardo Giordano Paterno, Paulo Eduardo Narcizo de Souza, Ana Paula Bastos, Emanuel Adelino Medeiros Damasceno, Fabiane Hiratsuka Veiga-Souza, Ricardo Bentes de Azevedo and Sônia Nair Báo

    Citation: Journal of Nanobiotechnology 2018 16:9

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  7. Content type: Research

    Trueperella pyogenes is a commensal and opportunistic pathogen that normally causes mastitis, liver abscesses and pneumonia of economically important livestock. To develop efficacious and potent vaccine against T...

    Authors: Ting Huang, Xuhao Song, Jie Jing, Kelei Zhao, Yongmei Shen, Xiuyue Zhang and Bisong Yue

    Citation: Journal of Nanobiotechnology 2018 16:8

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  8. Content type: Research

    Pancreatic cancer remains the leading cause of cancer-related deaths, the existence of cancer stem cells and lack of highly efficient early detection may account for the poor survival rate. Gadolinium ion-dope...

    Authors: Yong Han, Yanli An, Gang Jia, Xihui Wang, Chen He, Yinan Ding and Qiusha Tang

    Citation: Journal of Nanobiotechnology 2018 16:7

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  9. Content type: Research

    Gold nanoparticles are useful candidate for drug delivery applications and are associated with enhancement in the bioavailability of coated drugs and/or therapeutic agent. Since, heterocyclic compounds are kno...

    Authors: Ayaz Anwar, Sadia Khalid, Samina Perveen, Shakil Ahmed, Ruqaiyyah Siddiqui, Naveed Ahmed Khan and Muhammad Raza Shah

    Citation: Journal of Nanobiotechnology 2018 16:6

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  10. Content type: Correction

    Following publication of our article [1], we became aware that Roberto Di Gesù had been omitted from the list of authors. The corrected author list and authors’ contribution statement appear below. We apologize f...

    Authors: Roberto Di Gesù, Maria Luisa Bondì, Antonina Azzolina, Emanuela Fabiola Craparo, Chiara Botto, Erika Amore, Gaetano Giammona and Melchiorre Cervello

    Citation: Journal of Nanobiotechnology 2018 16:3

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    The original article was published in Journal of Nanobiotechnology 2014 12:21

  11. Content type: Research

    Treatment of severe or chronic skin wounds is an important challenge facing medicine and a significant health care burden. Proper wound healing is often affected by bacterial infection; where biofilm formation...

    Authors: Mario Alberto Pérez-Díaz, Phaedra Silva-Bermudez, Binisa Jiménez-López, Valentín Martínez-López, Yaaziel Melgarejo-Ramírez, Ana Brena-Molina, Clemente Ibarra, Isabel Baeza, M. Esther Martínez-Pardo, M. Lourdes Reyes-Frías, Erik Márquez-Gutiérrez, Cristina Velasquillo, Gabriel Martínez-Castañon, Fidel Martinez-Gutierrez and Roberto Sánchez-Sánchez

    Citation: Journal of Nanobiotechnology 2018 16:2

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  12. Content type: Research

    The results showed that the deciding factor is the culture medium in which the bacteria and the graphene oxide (GO) are incubated at the initial manipulation step. These findings allow better use of GO and GO-...

    Authors: Ping-Ching Wu, Hua-Han Chen, Shih-Yao Chen, Wen-Lung Wang, Kun-Lin Yang, Chia-Hung Huang, Hui-Fang Kao, Jui-Cheng Chang, Chih-Li Lilian Hsu, Jiu-Yao Wang, Ting-Mao Chou and Wen-Shuo Kuo

    Citation: Journal of Nanobiotechnology 2018 16:1

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  13. Content type: Research

    Selenium (Se) is an indispensable trace element required for animals and humans, and extra Se-supplement is necessary, especially for those having Se deficiency. Recently, selenium nanoparticles (SeNPs), as a ...

    Authors: Kaikai Bai, Bihong Hong, Zhuan Hong, Jipeng Sun and Changsen Wang

    Citation: Journal of Nanobiotechnology 2017 15:92

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  14. Content type: Research

    Since the anticancer drugs have diverse inhibited mechanisms to the cancer cells, the use of two or more kinds of anticancer agents may achieve excellent therapeutic effects, especially to the drug-resistant t...

    Authors: Xiangrui Yang, Shichao Wu, Wanyi Xie, Anran Cheng, Lichao Yang, Zhenqing Hou and Xin Jin

    Citation: Journal of Nanobiotechnology 2017 15:91

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  15. Content type: Research

    The insufficient understanding of unintended biological impacts from nanomaterials (NMs) represents a serious impediment to their use for scientific, technological, and medical applications. While previous stu...

    Authors: Sheenah L. Bryant, Josh E. Eixenberger, Steven Rossland, Holly Apsley, Connor Hoffmann, Nisha Shrestha, Michael McHugh, Alex Punnoose and Daniel Fologea

    Citation: Journal of Nanobiotechnology 2017 15:90

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  16. Content type: Research

    Secondary caries are considered the main cause of dental restoration failure. In this context, anti-biofilm and bactericidal properties are desired in dental materials against pathogens such as Streptococcus muta...

    Authors: Agnese Bregnocchi, Elena Zanni, Daniela Uccelletti, Fabrizio Marra, Domenico Cavallini, Francesca De Angelis, Giovanni De Bellis, Maurizio Bossù, Gaetano Ierardo, Antonella Polimeni and Maria Sabrina Sarto

    Citation: Journal of Nanobiotechnology 2017 15:89

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  17. Content type: Research

    This work aimed to provide useful information on the use of nanoemulsions for the percutaneous administration of triptolide. Lipid nanosystems have great potential for transdermal drug delivery. Nanoemulsions ...

    Authors: Meng Yang, Yongwei Gu, Dishun Yang, Xiaomeng Tang and Jiyong Liu

    Citation: Journal of Nanobiotechnology 2017 15:88

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  18. Content type: Research

    Chemotherapeutic drugs used for cancer therapy frequently encounter multiple-drug resistance (MDR). Nanoscale carriers that can target tumors to accumulate and release drugs intracellularly have the greatest p...

    Authors: Yi Zhou, Huaying Wen, Liang Gu, Jijun Fu, Jiayi Guo, Lingran Du, Xiaoqin Zhou, Xiyong Yu, Yugang Huang and He Wang

    Citation: Journal of Nanobiotechnology 2017 15:87

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  19. Content type: Research

    Targeted superparamagnetic iron oxide (SPIO) nanoparticles have emerged as a promising biomarker detection tool for molecular magnetic resonance (MR) image diagnosis. To identify patients who could benefit fro...

    Authors: Huai-Lu Chen, Fei-Ting Hsu, Yu-Chieh Jill Kao, Hua-Shan Liu, Wan-Zhen Huang, Chia-Feng Lu, Ping-Huei Tsai, Ahmed Atef Ahmed Ali, Gilbert Aaron Lee, Ray-Jade Chen and Cheng-Yu Chen

    Citation: Journal of Nanobiotechnology 2017 15:86

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  20. Content type: Research

    Anti-angiogenic therapy has great potential for cancer therapy with several FDA approved formulations but there are considerable side effects upon the normal blood vessels that decrease the potential applicati...

    Authors: Pedro Pedrosa, Amelie Heuer-Jungemann, Antonios G. Kanaras, Alexandra R. Fernandes and Pedro V. Baptista

    Citation: Journal of Nanobiotechnology 2017 15:85

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  21. Content type: Research

    The cell source for transplantation therapy is always a prerequisite question to be solved in clinical applications. Neural cells are considered non-regenerable, which highly restrict their application in the ...

    Authors: Qingtong Yu, Jingjing Chen, Wenwen Deng, Xia Cao, Yan Wang, Jie Zhou, Wenqian Xu, Pan Du, Qiang Wang, Jiangnan Yu and Ximing Xu

    Citation: Journal of Nanobiotechnology 2017 15:82

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  22. Content type: Review

    Aptamers are short non-coding, single-stranded oligonucleotides (RNA or DNA) developed through Systematic Evolution of Ligands by Exponential enrichment (SELEX) in vitro. Similar to antibodies, aptamers can bi...

    Authors: Mei Liu, Xiaocheng Yu, Zhu Chen, Tong Yang, Dandan Yang, Qianqian Liu, Keke Du, Bo Li, Zhifei Wang, Song Li, Yan Deng and Nongyue He

    Citation: Journal of Nanobiotechnology 2017 15:81

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  23. Content type: Research

    Increasing evidences indicate that exposure to multi-walled carbon nanotubes (MWCNTs) could induce adverse vascular effects, but the role of length of MWCNTs in determining the toxic effects is less studied. T...

    Authors: Jimin Long, Yafang Xiao, Liangliang Liu and Yi Cao

    Citation: Journal of Nanobiotechnology 2017 15:80

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  24. Content type: Research

    When evaluating the toxicity of engineered nanomaterials (ENMS) it is important to use multiple bioassays based on different mechanisms of action. In this regard we evaluated the use of gene expression and com...

    Authors: Donald H. Atha, Amber Nagy, Andrea Steinbrück, Allison M. Dennis, Jennifer A. Hollingsworth, Varsha Dua, Rashi Iyer and Bryant C. Nelson

    Citation: Journal of Nanobiotechnology 2017 15:79

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  25. Content type: Research

    Zero-valent iron nanoparticles (ZVI NPs) have been used extensively for the remediation of contaminated soil and groundwater. Owing to their large active surface area, they serve as strong and effective reduct...

    Authors: Yi-Huang Hsueh, Ping-Han Tsai, Kuen-Song Lin, Wan-Ju Ke and Chao-Lung Chiang

    Citation: Journal of Nanobiotechnology 2017 15:77

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  26. Content type: Research

    Stimuli-responsive polymer materials are a new kind of intelligent materials based on the concept of bionics, which exhibits more significant changes in physicochemical properties upon triggered by tiny enviro...

    Authors: Yuan Wang, Xue-Yin Zhang, Yan-Ling Luo, Feng Xu, Ya-Shao Chen and Yu-Yu Su

    Citation: Journal of Nanobiotechnology 2017 15:76

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  27. Content type: Research

    Biologics magnetics nanoparticles, magnetosomes, attract attention because of their magnetic characteristics and potential applications. The aim of the present study was to develop and characterize novel magne...

    Authors: Yasmina Hamdous, Imène Chebbi, Chalani Mandawala, Raphael Le Fèvre, François Guyot, Olivier Seksek and Edouard Alphandéry

    Citation: Journal of Nanobiotechnology 2017 15:74

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  28. Content type: Research

    Multimodal nanomaterials are useful for providing enhanced diagnostic information simultaneously for a variety of in vivo imaging methods. According to our research findings, these multimodal nanomaterials off...

    Authors: Shin-Woo Ha, Hee-Sang Cho, Young Il Yoon, Moon-Sun Jang, Kwan Soo Hong, Emmanuel Hui, Jung Hee Lee and Tae-Jong Yoon

    Citation: Journal of Nanobiotechnology 2017 15:73

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  29. Content type: Research

    RT-qPCR is routinely used in expression profiling of toxicity pathway genes. However, genetic and molecular level studies used to determine, understand and clarify potential risks of engineered nanomaterials (...

    Authors: Natasha M. Sanabria and Mary Gulumian

    Citation: Journal of Nanobiotechnology 2017 15:72

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  30. Content type: Methodology

    Intrinsic iron in biological tissues frequently precludes unambiguous the identification of iron oxide nanoparticles when iron-based detection methods are used. Here we report the full methodology for synthesi...

    Authors: Angela Ariza de Schellenberger, Ralf Hauptmann, Jason M. Millward, Eyk Schellenberger, Yuske Kobayashi, Matthias Taupitz, Carmen Infante-Duarte, Jörg Schnorr and Susanne Wagner

    Citation: Journal of Nanobiotechnology 2017 15:71

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  31. Content type: Research

    Due to their natural tendency to self-assemble, proteins and peptides are important components for organic nanotechnology. One particular class of peptides of recent interest is those that form amyloid fibrils...

    Authors: Alexander P. M. Guttenplan, Laurence J. Young, Dijana Matak-Vinkovic, Clemens F. Kaminski, Tuomas P. J. Knowles and Laura S. Itzhaki

    Citation: Journal of Nanobiotechnology 2017 15:70

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  32. Content type: Research

    The continuing spread of the newly emerged H7N9 virus among poultry in China, as well as the possibility of human-to-human transmission, has attracted numerous efforts to develop an effective vaccine against H...

    Authors: Ngoc Bich Pham, Thuong Thi Ho, Giang Thu Nguyen, Thuy Thi Le, Ngoc Thu Le, Huan-Cheng Chang, Minh Dinh Pham, Udo Conrad and Ha Hoang Chu

    Citation: Journal of Nanobiotechnology 2017 15:69

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  33. Content type: Research

    In this study, we grafted bromo-terminated poly(N-isopropylacrylamide) (PNIPAAm) brushes onto thin gold films deposited on silicon, and then reacted with NaN3 to produce azido-terminated PNIPAAm brushes. A probe ...

    Authors: Yi-Zu Liu, May-Show Chen, Chih-Chia Cheng, Shih-Hsun Chen and Jem-Kun Chen

    Citation: Journal of Nanobiotechnology 2017 15:68

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  34. Content type: Research

    Advanced stage cancer treatments are often invasive and painful—typically comprised of surgery, chemotherapy, and/or radiation treatment. Low transport efficiency during systemic chemotherapy may require high ...

    Authors: Lee B. Sims, Maya K. Huss, Hermann B. Frieboes and Jill M. Steinbach-Rankins

    Citation: Journal of Nanobiotechnology 2017 15:67

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  35. Content type: Research

    Tyrosine kinase inhibitors (TKIs) that act against the epithelial growth factor receptor (EGFR) were once widely used in chemotherapy for many human cancers. However, acquired chemoresistance occurred in almos...

    Authors: Yan Zheng, Chang Su, Liang Zhao and Yijie Shi

    Citation: Journal of Nanobiotechnology 2017 15:66

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  36. Content type: Review

    Orthopaedic and dental implants have become a staple of the medical industry and with an ageing population and growing culture for active lifestyles, this trend is forecast to continue. In accordance with the ...

    Authors: Alka Jaggessar, Hesam Shahali, Asha Mathew and Prasad K. D. V. Yarlagadda

    Citation: Journal of Nanobiotechnology 2017 15:64

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  37. Content type: Research

    Ultrasound molecular imaging is a novel diagnostic approach for tumors, whose key link is the construction of targeted ultrasound contrast agents. However, available targeted ultrasound contrast agents for mol...

    Authors: Lianhua Zhu, Yanli Guo, Luofu Wang, Xiaozhou Fan, Xingyu Xiong, Kejing Fang and Dan Xu

    Citation: Journal of Nanobiotechnology 2017 15:63

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  38. Content type: Research

    The parasitic disease malaria remains a major global public health concern and no truly effective vaccine exists. One approach to the development of a malaria vaccine is to target the asexual blood stage that ...

    Authors: Christopher P. Karch, Tais A. P. F. Doll, Sara M. Paulillo, Issa Nebie, David E. Lanar, Giampietro Corradin and Peter Burkhard

    Citation: Journal of Nanobiotechnology 2017 15:62

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  39. Content type: Short Communication

    Moth-eye nanostructures are a well-known example of biological antireflective surfaces formed by pseudoregular arrays of nipples and are often used as a template for biomimetic materials. Here, we provide morp...

    Authors: Mikhail Kryuchkov, Jannis Lehmann, Jakob Schaab, Vsevolod Cherepanov, Artem Blagodatski, Manfred Fiebig and Vladimir L. Katanaev

    Citation: Journal of Nanobiotechnology 2017 15:61

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  40. Content type: Research

    Pollen Typhae Carbonisata (PTC) is a type of calcined herb drug that has been used as a hemostatic medicine to promote hemostasis for thousands of years. In this study, we discovered a...

    Authors: Xin Yan, Yan Zhao, Juan Luo, Wei Xiong, Xiaoman Liu, Jinjun Cheng, Yongzhi Wang, Meiling Zhang and Huihua Qu

    Citation: Journal of Nanobiotechnology 2017 15:60

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  41. Content type: Research

    Most methods for monitoring glucose level require an external energy source which may limit their application, particularly in vivo test. Bioluminescence technique offers an alternative way to provide emission...

    Authors: Longyan Chen, Longyi Chen, Michelle Dotzert, C. W. James Melling and Jin Zhang

    Citation: Journal of Nanobiotechnology 2017 15:59

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  42. Content type: Research

    LiCoO2 is one of the most used cathode materials in Li-ion batteries. Its conventional synthesis requires high temperature (>800 °C) and long heating time (>24 h) to obtain the micronscale rhombohedral layered hi...

    Authors: Jean-Pierre Brog, Aurélien Crochet, Joël Seydoux, Martin J. D. Clift, Benoît Baichette, Sivarajakumar Maharajan, Hana Barosova, Pierre Brodard, Mariana Spodaryk, Andreas Züttel, Barbara Rothen-Rutishauser, Nam Hee Kwon and Katharina M. Fromm

    Citation: Journal of Nanobiotechnology 2017 15:58

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