Figure 4
From: Fabrication of PLGA nanoparticles with a fluidic nanoprecipitation system
The diameter of PLGA nanoparticles can be controlled by varying the methanol concentrations (v/v) in the dispersing phase. Diameter of PLGA nanoparticles fabricated using 20%, 50% or 80% v/v methanol in the dispersing phase of the FNPS. The flow rate of the dispersing channel was maintained at 50 ml/minute. Samples were imaged by SEM without prior filtration. The diameter of the particles was calculated by using ImageJ. For each sample, the mean diameter was calculated based on the measurements of 100 randomly chosen particles.