Fig. 3

Magnetic nanoparticles (MNPs) functionalization by homing molecules (RGD-peptide) increases particles elimination and prevents non-specific accumulation in mice healthy organs. Pharmacokinetic of aminosilane coated magnetic nanoparticles (MNP@NH2) and their derivatives functionalized by RGD peptide (MNP@RGD) 8 h after intravenous injection (a). Structure of magnetic nanoparticles functionalized by RGD peptide and fluorescent probe DYE 800 CW (b). Biodistribution of MNP@NH₂ and MNP@RGD 8 h after intravenous injection (c)