Target moiety | Nanoformulation | Active compound | Indication | Therapy | Reference |
---|---|---|---|---|---|
Epidermal growth factor receptor | Peptide-targeted gold nanoparticles | Pc 4 | Brain cancer | Photodynamic therapy | [213] |
Epidermal growth factor receptor | PLGA nanoparticles | Tylocrebine | Several types of tumors, including epidermoid cancer | Chemotherapy | [214] |
Fibrin-associated plasma proteins | CREKA-conjugated dextran-coated iron oxide nanoparticles | Iron oxide NPs | Non-small lung cancer | Hyperthermia | [67] |
Fibrin-associated plasma proteins | CREKA-conjugated liposomes | Doxorubicin | Breast cancer | Chemotherapy | [68] |
Folate receptors | PLGA polymeric nanoparticles | Doxorubicin | Breast cancer | Chemotherapy | [47] |
Folate receptors | Cobalt ferrite nanoparticles | Hematoporphyrin | Several types of FR-positive tumors | Photodynamic therapy | [65] |
Folate receptors | Deoxycholic acid-O-carboxymethylated chitosan nanoparticles | Paclitaxel | Breast cancer | Chemotherapy | [25] |
IL-13RÉ‘2 | Liposomes | Doxorubicin | Glioblastoma multiforme | Chemotherapy | [215] |
Integrin receptors | RGD-modified liposomes | Paclitaxel | Hepatocellular carcinoma | Chemotherapy | [216] |
LHRH receptor | Gold nanorods | Goserelin | Prostate cancer | Radiotherapy | [217] |
Transferrin receptors | PEGylated gold nanoparticles | AuNPs | Mouse neuroblastoma | Chemotherapy | [61] |
Transferrin receptors | VitE TPGS-encapsulated micelles | Docetaxel | Breast cancer | Chemotherapy | [34] |
Transferrin receptors | PLGA polymeric nanoparticles | Methotrexate | Brain cancer | Chemotherapy | [33] |