Table 2 The minimal inhibitory concentrations (MIC) of imipenem/cilastatin loaded polycaprolactone (IMP/PCL), and imipenem/cilastatin loaded polylactide-co-glycolide (IMP/PLGA) compared to imipenem/(IMP) against Klebsiella pneumoniae and Pseudomonas aeruginosa isolates
MIC (µg/ml) | |||
|---|---|---|---|
IMP/PCL | IMP/PLGA | IMP | |
Klebsiella pneumoniae | |||
ATCC4352 | 0.6 | 1.25 | 0.6 |
KMU5.5 | 5 | 312.5 | 312.5 |
KMU4.5 | 2.5 | 156.5 | 625 |
KMU2.3 | 2.5 | 80 | 80 |
Pseudomonas aeruginosa | |||
PAO1 | 1.25 | 1.25 | 1.25 |
PWMU2.3 | 20 | 312.5 | 625 |
PUMU2.3 | 10 | 625 | 625 |
PSMU8.0 | 1.25 | 20 | 40 |