Fig. 1
From: A retro-inverso cell-penetrating peptide for siRNA delivery
Structural characterization of RICK and isoforms. a, b Circular dichroism (CD) profiles of CADY-K, d-cady-k and RICK in solution, associated to siRNA anti-FLuc at a 20/1 molar ratio (R = 20) and in the presence of LUVs composed of DOPC/SM/Chol (2:2:1) and at a final lipid/peptide ratio of 5 (r = 5). c, d CD spectra of CADY-K/d-cady-k and CADY-K/RICK mixtures in solution at an equimolar ratio and in the presence of siRNA at a final peptide:siRNA ratio R = 20. e, f Effects of heating/cooling cycle from 22 to 80 °C on CD spectra of RICK and CADY-K. CD signals are expressed in Ellipticity